Projects per year
Personal profile
Chinese Name
Biography
Dr. Chong obtained his MPhil and PhD in Immunology from the Department of Paediatrics and Adolescent Medicine at The University of Hong Kong. He received his postdoctoral training in immunology from the National Eye Institute at National Institutes of Health (NIH) in Bethesda, MD, USA. After that, he was appointed as the Associate Professor at the Key State Laboratory of Ophthalmology, Sun Yat-sen University in Guangzhou, China. He joined the School of Chinese Medicine, Hong Kong Baptist University, as the Associate Professor in 2022.
Dr. Chong's research centers on the cellular and molecular mechanism involved in immunoregulation and autoimmunity, and discovering novel therapeutic drug for autoimmune diseases. His works on autoimmunity have been well recognized and published in prestigious journals, including Immunity, Journal of Experimental Medicine, Journal of Autoimmunity, Hepatology and Journal of Infection.
Research Interests
Dr Chong’s interest is in cellular and molecular mechanisms involved in regulating immune responses in autoimmune diseases. To better dissect the basic mechanisms involved, we used various animal models, including experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune uveitis (EAU) to understand the disease pathogenesis. The goal is to translate our observations from these studies for the development of novel approaches for immunotherapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- QR180 Immunology
- QH426 Genetics
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Collaborations and top research areas from the last five years
Projects
- 1 Not started
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Regulatory T cell intravitreal delivery using hyaluronan methylcellulose hydrogel improves therapeutic efficacy in experimental autoimmune uveitis
Zhang, T., Han, X., Zhong, Y., Kam, H. T., Qiao, D., Chen, Z., Chan, K. W. Y., Chong, W. P. & Chen, J., Aug 2023, In: Biomaterials Advances. 151, 213496.Research output: Contribution to journal › Journal article › peer-review
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Induction of antigen-specific Treg cells in treating autoimmune uveitis via bystander suppressive pathways without compromising anti-tumor immunity
Chen, Z., Zhang, T., Kam, H. T., Qiao, D., Jin, W., Zhong, Y., Zhou, M., Zhou, H., Chong, W. P., Chen, W. & Chen, J., Aug 2021, In: EBioMedicine. 70, 12 p., 103496.Research output: Contribution to journal › Journal article › peer-review
Open Access4 Citations (Scopus) -
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
Chong, W. P., Mattapallil, M. J., Raychaudhuri, K., Bing, S. J., Wu, S., Zhong, Y., Wang, W. W., Chen, Z., Silver, P. B., Jittayasothorn, Y., Chan, C. C., Chen, J., Horai, R. & Caspi, R. R., 18 Aug 2020, In: Immunity. 53, 2, p. 384-397.e5 19 p.Research output: Contribution to journal › Journal article › peer-review
Open Access81 Citations (Scopus) -
Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection
Tu, X., Chong, W. P., Zhai, Y., Zhang, H., Zhang, F., Wang, S., Liu, W., Wei, M., Siu, N. H. O., Yang, H., Yang, W., Cao, W., Lau, Y. L., He, F. & Zhou, G., Jul 2015, In: Journal of Infection. 71, 1, p. 101-109 9 p.Research output: Contribution to journal › Journal article › peer-review
Open Access71 Citations (Scopus) -
NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ-IL-27 axis
Chong, WP., van, P. N., Chen, J., Silver, P. B., Jittayasothorn, Y., Mattapallil, M. J., Germain, R. N. & Caspi, R. R., 7 Sept 2015, In: The Journal of experimental medicine. 212, 10, p. 1739-1752Research output: Contribution to journal › Journal article › peer-review
59 Citations (Scopus)
Prizes
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The 2020 William E. Paul Best Paper in Cytokine Research Award
CHONG, Wai Po (Recipient), 10 Jun 2021
Prize: Award
Activities
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DOVS Lecture: Th17/Treg Balance in Retinal Inflammation
Wai Po CHONG (Plenary/keynote speaker)
19 May 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Frontiers in Neurology (Journal)
Wai Po CHONG (Guest editor)
1 Feb 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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International Journal of Molecular Sciences (Journal)
Wai Po CHONG (Guest editor)
1 Nov 2022Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
Wai Po CHONG (Speaker)
10 Jun 2021Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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DOVS Lecture: Regulating autoreactive T cells in ocular inflammation
Wai Po CHONG (Plenary/keynote speaker)
30 Mar 2021Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
Press/Media
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Hong Kong young professor: Hong Kong young people have a lot of potential to be successful in mainland China
10/09/19
1 item of Media coverage
Press/Media