Projects per year
Personal profile
Chinese Name
Biography
Dr. Chong obtained his MPhil and PhD in Immunology from the Department of Paediatrics and Adolescent Medicine at The University of Hong Kong. He received his postdoctoral training in immunology from the National Eye Institute at National Institutes of Health (NIH) in Bethesda, MD, USA. After that, he was appointed as the Associate Professor at the Key State Laboratory of Ophthalmology, Sun Yat-sen University in Guangzhou, China. He joined the School of Chinese Medicine, Hong Kong Baptist University, as the Associate Professor in 2022.
Dr. Chong's research centers on the cellular and molecular mechanism involved in immunoregulation and autoimmunity, and discovering novel therapeutic drug for autoimmune diseases. His works on autoimmunity have been well recognized and published in prestigious journals, including Immunity, Journal of Experimental Medicine, Journal of Autoimmunity, Hepatology and Journal of Infection.
Research Interests
Dr Chong’s interest is in cellular and molecular mechanisms involved in regulating immune responses in autoimmune diseases. To better dissect the basic mechanisms involved, we used various animal models, including experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune uveitis (EAU) to understand the disease pathogenesis. The goal is to translate our observations from these studies for the development of novel approaches for immunotherapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- QR180 Immunology
- QH426 Genetics
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Collaborations and top research areas from the last five years
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The role of Interleukin 24 in regulating ocular inflammation: a novel cytokine for the treatment of autoimmune uveitis
CHONG, W. P. (PI), REN, K. (Collaborator), Caspi, R. R. (Collaborator), Calvin CP , P. (Collaborator) & Chu, W. K. (Collaborator)
1/12/24 → 30/11/26
Project: Research project
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Equipment Matching Fund - High-performance Slide Scanner
LIU, J. (PI), LI, F. (CoI), YU, Y. (CoI), XU, J. (CoI), FU, X. (CoI), WONG, H. L. X. (CoI), KWAN, H. Y. (CoI) & CHONG, W. P. (CoI)
26/03/24 → 25/03/26
Project: Research project
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细胞因子 IL-24 通过抑制自身反应性 T 细胞和视网膜色素上皮改善实验性自身免疫性葡萄膜炎
CHONG, W. P. (PI)
1/01/24 → 31/12/27
Project: Research project
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The role of Interleukin 24 in regulating ocular inflammation: a novel cytokine for the treatment of autoimmune uveitis
CHONG, W. P. (PI) & Caspi, R. (Collaborator)
1/09/23 → 30/06/24
Project: Research project
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NK-based Immunotherapy for glioblastoma using injectable hydrogel under MRI guidance.
CHONG, W. P. (PI) & Caspi, R. (Collaborator)
1/01/23 → 30/06/24
Project: Research project
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Regulatory T cell intravitreal delivery using hyaluronan methylcellulose hydrogel improves therapeutic efficacy in experimental autoimmune uveitis
Zhang, T., Han, X., Zhong, Y., Kam, H. T., Qiao, D., Chen, Z., Chan, K. W. Y., Chong, W. P. & Chen, J., Aug 2023, In: Biomaterials Advances. 151, 213496.Research output: Contribution to journal › Journal article › peer-review
4 Citations (Scopus) -
Induction of antigen-specific Treg cells in treating autoimmune uveitis via bystander suppressive pathways without compromising anti-tumor immunity
Chen, Z., Zhang, T., Kam, H. T., Qiao, D., Jin, W., Zhong, Y., Zhou, M., Zhou, H., Chong, W. P., Chen, W. & Chen, J., Aug 2021, In: EBioMedicine. 70, 12 p., 103496.Research output: Contribution to journal › Journal article › peer-review
Open Access15 Citations (Scopus) -
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
Chong, W. P., Mattapallil, M. J., Raychaudhuri, K., Bing, S. J., Wu, S., Zhong, Y., Wang, W. W., Chen, Z., Silver, P. B., Jittayasothorn, Y., Chan, C. C., Chen, J., Horai, R. & Caspi, R. R., 18 Aug 2020, In: Immunity. 53, 2, p. 384-397.e5 19 p.Research output: Contribution to journal › Journal article › peer-review
Open Access118 Citations (Scopus) -
Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection
Tu, X., Chong, W. P., Zhai, Y., Zhang, H., Zhang, F., Wang, S., Liu, W., Wei, M., Siu, N. H. O., Yang, H., Yang, W., Cao, W., Lau, Y. L., He, F. & Zhou, G., Jul 2015, In: Journal of Infection. 71, 1, p. 101-109 9 p.Research output: Contribution to journal › Journal article › peer-review
Open Access76 Citations (Scopus) -
NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ-IL-27 axis
Chong, W., van, P. N., Chen, J., Silver, P. B., Jittayasothorn, Y., Mattapallil, M. J., Germain, R. N. & Caspi, R. R., 7 Sept 2015, In: Journal of Experimental Medicine. 212, 10, p. 1739-1752Research output: Contribution to journal › Journal article › peer-review
64 Citations (Scopus)
Prizes
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The 2020 William E. Paul Best Paper in Cytokine Research Award
CHONG, W. P. (Recipient), 10 Jun 2021
Prize: Award
Activities
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Frontiers in Immunology (Journal)
CHONG, W. P. (Guest editor)
26 Jan 2024 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Discover Immunity (Journal)
CHONG, W. P. (Member of editorial board)
15 Jan 2024 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Frontiers in Neurology (Journal)
CHONG, W. P. (Guest editor)
1 Feb 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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DOVS Lecture: Th17/Treg Balance in Retinal Inflammation
CHONG, W. P. (Plenary/keynote speaker)
19 May 2023Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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World Federation of Chinese Medicine Societies (External organisation)
CHONG, W. P. (General member)
1 Dec 2023 → 31 Dec 2028Activity: Membership › Membership of board/committee/council
Press/Media
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Hong Kong young professor: Hong Kong young people have a lot of potential to be successful in mainland China
10/09/19
1 item of Media coverage
Press/Media