Poly (ADP-ribose) Polymerase 1 (PARP1) Inhibition Promotes Pulmonary Metastasis of Osteosarcoma by Boosting Ezrin Phosphorylation

Xiaoqiu WU

Chinese Medicine - Teaching and Research Division

Student thesis: Doctoral Thesis

Date of Award	27 Sept 2021
Original language	English
Supervisor	Ge ZHANG (Supervisor)

User-Defined Keywords

Osteosarcoma
pulmonary metastasis
PARP inhibitor
ezrin
combination therapy

Cite this

Documents

Full Text
File: application/pdf, 35.5 MB
Type: Thesis
Embargo End Date: 27 Sept 2022

Abstract & TOC
File: application/pdf, 111 KB
Type: Supplementary materials
Embargo End Date: 27 Sept 2022

Related content

Projects / Grants
A Novel Nucleolin Aptamer-Maytansine Conjugate for Chemo-resistant Ovarian Cancer
Project: Research project
Osteosarcoma-specific delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in a patient-derived xenograft model
Project: Research project
Toward the next generation of smart anti-tumor drugs: a highly water-soluble nucleolin aptamer-paclitaxel conjugate with a serum-stable linker for tumor-specific targeting in ovarian cancer
Project: Research project

'