Analysis of biomarkers of age-related diseases by total internal reflection fluorescence microscopy

  • Hei Nga Chan

Student thesis: Doctoral Thesis


Total internal reflection fluorescence microscopy (TIRFM) has been widely applied for the study of biomolecules because of their ability to quantify biomolecules in a sample pretreatment and enrichment free manner, when compared with those costly, sample consuming and labor intensive conventional detection assay. Here, we have applied the TIRFM imaging system for the direct quantification and analysis of the biomarkers for the age-related diseases. Three research works on the quantification and study of biomarkers with the aid of TIRFM were herein described.

Date of Award1 Jun 2018
Original languageEnglish
SupervisorHung Wing LI (Supervisor)

User-Defined Keywords

  • Older people
  • Diseases
  • Total internal reflection (Optics)
  • Fluorescence microscopy

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