Yoga training modulates adipokines in adults with high-normal blood pressure and metabolic syndrome

Rashmi-Supriya -, Angus P. Yu, Paul H. Lee, Christopher W. Lai, Kenneth K. Cheng, Sonata Y. Yau, Lawrence W. Chan, Benjamin Y. Yung, Parco M. Siu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Metabolic syndrome (MetS) is associated with diabetes mellitus and cardiovascular diseases. Our previous study indicated that people with MetS showed a decrease in waist circumference and a decreasing trend in blood pressure after 1-year yoga. This study investigated the effect of yoga on MetS people with high-normal blood pressure by exploring modulations in proinflammatory adipokines (leptin, chemerin, visfatin, and plasminogen activator inhibitor-1 or PAI-1) and an anti-inflammatory adipokine (adiponectin). A total of 97 Hong Kong Chinese individuals aged 57.6 ± 9.1 years with MetS and high-normal blood pressure were randomly assigned to control (n = 45) and yoga groups (n = 52). Participants in the control group were not given any intervention but were contacted monthly to monitor their health status. Participants in the yoga group underwent a yoga training program with three 1-hour yoga sessions weekly for 1 year. The participants’ sera were harvested and assessed for adipokines. Generalized estimating equation (GEE) was used to examine the interaction effect between 1-year time (pre vs post), and intervention (control vs yoga). GEE analyses revealed significant interaction effects between 1-year time and yoga intervention for the decreases in leptin and chemerin and the increase in adiponectin concentration in the sera examined. These results demonstrated that 1-year yoga training decreased proinflammatory adipokines and increased anti-inflammatory adipokine in adults with MetS and high-normal blood pressure. These findings support the beneficial role of yoga in managing MetS by favorably modulating adipokines.
Original languageEnglish
Pages (from-to)1130-1138
Number of pages9
JournalScandinavian Journal of Medicine and Science in Sports
Issue number3
Publication statusPublished - Mar 2018


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