Xanthones with growth inhibition against HeLa cells from Garcinia xipshuanbannaensis

Quan Bin Han, Nian Yun Yang, Hong Lei Tian, Chun Feng Qiao, Jing Zheng Song, Donald C. Chang, Shi Lin Chen, Kathy Q. Luo*, Hong Xi Xu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

88 Citations (Scopus)

Abstract

Eight prenylated xanthones, bannaxanthones A-H (1-8), together with seven known compounds, were isolated from the acetone extract of the twigs of Garcinia xipshuanbannaensis. Their structures were elucidated by spectroscopic data interpretation. The cytotoxic activities of these compounds were evaluated using the MTT method. The results showed that xanthones with an unsaturated prenyl group had stronger cytotoxic activity against cancer cells, whereas those with hydroxylated prenyl groups had none.

Original languageEnglish
Pages (from-to)2187-2192
Number of pages6
JournalPhytochemistry
Volume69
Issue number11
DOIs
Publication statusPublished - Aug 2008

Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

User-Defined Keywords

  • Bannaxanthones
  • Clusiaceae
  • Garcinia xipshuanbannaensis
  • Growth inhibition
  • HeLa cells
  • Xanthone

Fingerprint

Dive into the research topics of 'Xanthones with growth inhibition against HeLa cells from Garcinia xipshuanbannaensis'. Together they form a unique fingerprint.

Cite this