Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: photoluminescent properties and cytotoxicities

Dik Lung Ma, Tina Yuen Ting Shum, Fuyi Zhang, Chi Ming Che*, Mengsu Yang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

128 Citations (Scopus)

Abstract

Platinum(II) terpyridine complexes with glycosylated acetylide and arylacetylide ligands bind to DNA with binding constants ∼105 mol−1 dm3; the glycosylated arylacetylide complexes exhibit emission at λmax ≈ 620 nm in water and are up to ∼100-times higher in potency than the clinical cisplatin drug in killing cancer cells.

Original languageEnglish
Pages (from-to)4675-4677
Number of pages3
JournalChemical Communications
Issue number37
Early online date23 Aug 2005
DOIs
Publication statusPublished - 7 Oct 2005
Externally publishedYes

Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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