TY - JOUR
T1 - Water soluble Ln(III)-based metallopolymer with AIE-active and ACQ-effect lanthanide behaviors for detection of nanomolar pyrophosphate
AU - Zhang, Zhao
AU - Chang, Hui
AU - Kang, Yifan
AU - Li, Xinping
AU - Jiang, Huie
AU - Xue, Bailiang
AU - Wang, Yaoyu
AU - Lü, Xingqiang
AU - ZHU, Xunjin
N1 - Funding Information:
This work was supported by National Natural Science Foundation of China ( 21703131 , 31370578 ), Doctoral Scientific Research Foundation of Shaanxi University of Science & Technology ( 2016BJ-40 ), and State Key Laboratory of Pulp and Paper Engineering ( 201821 ).
PY - 2019/3/1
Y1 - 2019/3/1
N2 - In this study, a polymerizable terpyridine 2-(4-(4-(4-vinylbenzyloxy)phenyl)-6-(pyridin-2-yl)pyridin-2-yl)pyridine was synthesized, with N-(2-hydroxyethyl)acrylamide (HEAA) used to obtain an amphipathic polymer (Poly) through free radical polymerization. Then, Poly was coordinated with LnCl3 or Ln(ABM)3(H2O)2 (ABM = 4,4,4-trifluoro-1-phenylbutane-1,3-dione; Ln = Eu or Gd) in an equimolar ratio and a series of terpyridine-based Ln(III)-metallopolymer Poly-Eu or Poly-Eu-ABM obtained. The results strongly suggested that Poly-Eu exhibited aggregation-induced lanthanide emission. In contrast, after the introduction of a secondary sensitizer, ABM to Poly-Eu, aggregation-caused quenching effects were observed in Poly-Eu-ABM. In addition, both Poly-Eu and Poly-Eu-ABM were applied as fluorescence sensors to selectively detect pyrophosphate (PPi) among a series of different anions and the detection limit found to be at the nanomolar scale. Furthermore, high PPi sensitivity and selectively, low toxicity, and water solubility of this metallopolymer matrix Poly-Eu-ABM were used to detect PPi in living cells.
AB - In this study, a polymerizable terpyridine 2-(4-(4-(4-vinylbenzyloxy)phenyl)-6-(pyridin-2-yl)pyridin-2-yl)pyridine was synthesized, with N-(2-hydroxyethyl)acrylamide (HEAA) used to obtain an amphipathic polymer (Poly) through free radical polymerization. Then, Poly was coordinated with LnCl3 or Ln(ABM)3(H2O)2 (ABM = 4,4,4-trifluoro-1-phenylbutane-1,3-dione; Ln = Eu or Gd) in an equimolar ratio and a series of terpyridine-based Ln(III)-metallopolymer Poly-Eu or Poly-Eu-ABM obtained. The results strongly suggested that Poly-Eu exhibited aggregation-induced lanthanide emission. In contrast, after the introduction of a secondary sensitizer, ABM to Poly-Eu, aggregation-caused quenching effects were observed in Poly-Eu-ABM. In addition, both Poly-Eu and Poly-Eu-ABM were applied as fluorescence sensors to selectively detect pyrophosphate (PPi) among a series of different anions and the detection limit found to be at the nanomolar scale. Furthermore, high PPi sensitivity and selectively, low toxicity, and water solubility of this metallopolymer matrix Poly-Eu-ABM were used to detect PPi in living cells.
KW - AIE-active lanthanide behaviors
KW - Eu(III)-based metallopolymer
KW - Nanomolar scale
KW - PPi Probes
KW - Water-soluble
UR - http://www.scopus.com/inward/record.url?scp=85058933462&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2018.11.118
DO - 10.1016/j.snb.2018.11.118
M3 - Journal article
AN - SCOPUS:85058933462
SN - 0925-4005
VL - 282
SP - 999
EP - 1007
JO - Sensors and Actuators B: Chemical
JF - Sensors and Actuators B: Chemical
ER -