Versatile Physiological Functions of Plant GSK3-Like Kinases

Juan Mao*, Wenxin Li, Jing Liu, Jianming Li*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


The plant glycogen synthase kinase 3 (GSK3)-like kinases are highly conserved protein serine/threonine kinases that are grouped into four subfamilies. Similar to their mammalian homologs, these kinases are constitutively active under normal growth conditions but become inactivated in response to diverse developmental and environmental signals. Since their initial discoveries in the early 1990s, many biochemical and genetic studies were performed to investigate their physiological functions in various plant species. These studies have demonstrated that the plant GSK3-like kinases are multifunctional kinases involved not only in a wide variety of plant growth and developmental processes but also in diverse plant stress responses. Here we summarize our current understanding of the versatile physiological functions of the plant GSK3-like kinases along with their confirmed and potential substrates.

Original languageEnglish
Article number697
Number of pages17
Issue number5
Early online date8 May 2021
Publication statusPublished - May 2021

Scopus Subject Areas

  • Genetics
  • Genetics(clinical)

User-Defined Keywords

  • brassinosteroid signaling
  • protein phosphorylation
  • biotic/abiotic stress
  • stomata development
  • flowering
  • cell division/differentiation
  • cell expansion/elongation
  • root development
  • vascular differentiation
  • photomorphogenesis


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