TY - GEN
T1 - Using text mining to understand traditional Chinese medicine pathogenesis of nonalcoholic fatty liver disease
AU - Zhang, Hui Qin
AU - Li, Jian
AU - Zheng, Guang
AU - Jiang, Miao
AU - Li, Li
AU - Tan, Yong
AU - LYU, Aiping
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - Non-alcoholic fatty liver disease (NAFLD) is a kind of prevalence diseases. Traditional Chinese medicine (TCM) has better efficacy on treating NAFLD. But there are also not known about the critical pathogenesis and the corresponding biological factors. Regarding this, we addressed a text mining approach to analyze the pattern profile, rule of medication, and the pathological factors of NAFLD from the opening database (SinoMed and PubMed). Based on canonical data source, we have our data treatment scheduled in 4 steps: (1) data retrieving, (2) data pretreating, (3) data analyzing, and (4) data visualization. And according to the TCM theory of formulae-pattern-disease' correlation, we partly understand the possible TCM pathogenesis of NAFLD which linked biological process of lipid metabolism disorder, inflammation, and metabolic regulation confusion.
AB - Non-alcoholic fatty liver disease (NAFLD) is a kind of prevalence diseases. Traditional Chinese medicine (TCM) has better efficacy on treating NAFLD. But there are also not known about the critical pathogenesis and the corresponding biological factors. Regarding this, we addressed a text mining approach to analyze the pattern profile, rule of medication, and the pathological factors of NAFLD from the opening database (SinoMed and PubMed). Based on canonical data source, we have our data treatment scheduled in 4 steps: (1) data retrieving, (2) data pretreating, (3) data analyzing, and (4) data visualization. And according to the TCM theory of formulae-pattern-disease' correlation, we partly understand the possible TCM pathogenesis of NAFLD which linked biological process of lipid metabolism disorder, inflammation, and metabolic regulation confusion.
KW - Non-alcoholic liver disease
KW - Pathogenesis
KW - Text mining
UR - http://www.scopus.com/inward/record.url?scp=84894562245&partnerID=8YFLogxK
U2 - 10.1109/BIBM.2013.6732702
DO - 10.1109/BIBM.2013.6732702
M3 - Conference proceeding
AN - SCOPUS:84894562245
SN - 9781479913091
T3 - Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
SP - 311
EP - 314
BT - Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
T2 - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
Y2 - 18 December 2013 through 21 December 2013
ER -