Use of LC fingerprinting to evaluate the quality of Erxian decoction

Yong Mei Hu, Stephen Cho Wing Sze, Shou Xun Zhao, Yao Tong*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

High-performance liquid chromatography with diode-array detection has been used to evaluate the quality of Erxian decoction (EXD), a Chinese medicine prescription, by use of a combination of fingerprinting and simultaneous quantification of six marker compounds. The standard chromatographic fingerprint containing forty common peaks was constructed from seven batches of the EXD samples to evaluate batch-to-batch consistency. In addition, six representative bioactive markers were simultaneously quantified with good linearity, precision, repeatability, and accuracy. The fingerprint accompanied by quantification of the marker compounds can be used to evaluate the quality of EXD.
Original languageEnglish
Pages (from-to)613-618
Number of pages6
JournalChromatographia
Volume70
Issue number3-4
DOIs
Publication statusPublished - Aug 2009
Externally publishedYes

User-Defined Keywords

  • Column liquid chromatography
  • Diode-array detection
  • Erxian decoction
  • Traditional Chinese medicine
  • Quality evaluation
  • Fingerprint
  • Consistency

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