@inbook{71e3a7ae7c104308aed0f53965a9f75f,
title = "Upconversion Nanoparticle-Mediated Optogenetics",
abstract = "Upconversion nanoparticle-mediated optogenetics enables remote delivery of upconverted visible light from a near-infrared light source to targeted neurons or areas, with the precision of a pulse of laser light in vivo for effective deep-tissue neuromodulation. Compared to conventional optogenetic tools, upconversion nanoparticle-based optogenetic techniques are less invasive and cause reduced inflammation with minimal levels of tissue damage. In addition to the optical stimulation, this design offers simultaneously temperature recording in proximity to the stimulated area. This chapter strives to provide life science researchers with an introduction to upconversion optogenetics, starting from the fundamental concept of photon upconversion and nanoparticle fabrication to the current state-of-the-art of surface engineering and device integration for minimally invasive neuromodulation.",
keywords = "Infrared Rays, Nanoparticles, Neurons, Optogenetics, Photons",
author = "Zhigao Yi and ALL, {Angelo Homayoun} and Xiaogang Liu",
note = "Funding Information: This work was supported by the Singapore Ministry of Education (MOE2017-T2-2-110), Agency for Science, Technology and Research (A*STAR) (A1883c0011 and A1983c0038), National Research Foundation, Prime Minister?s Office, Singapore under the NRF Investigatorship programme (Award No. NRF-NRFI05-2019-0003), and National Natural Science Foundation of China (21771135).",
year = "2021",
month = jan,
day = "6",
doi = "10.1007/978-981-15-8763-4_44",
language = "English",
isbn = "9789811587627",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer Singapore",
pages = "641--657",
editor = "Hiromu Yawo and Hideki Kandori and Amane Koizumi and Ryoichiro Kageyama",
booktitle = "Optogenetics",
address = "Singapore",
edition = "2nd",
}