Uniform design applied to nonlinear multivariate calibration by ANN

Lin Zhang, Yi-Zeng Liang*, Jian-Hui Jiang, Ru-Qin Yu, Kai-Tai Fang

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

79 Citations (Scopus)


In this paper, a new experimental design called uniform design (UD) has been introduced as a promising candidate for experimental design in nonlinear multivariate calibration by ANN. In its application to ANN, the UD has the following merits:
    1. it is capable of producing samples with high representativeness;
    2. it imposes no strong assumption on the model; and
    3. it allows many levels for each factor.
A comparative study has been made among UD, orthogonal array design (OAD) and central composite design (CCD). The results by UD in simulated and real-fluorescence systems are satisfactory.
Original languageEnglish
Pages (from-to)65-77
Number of pages13
JournalAnalytica Chimica Acta
Issue number1
Publication statusPublished - 31 Aug 1998
Externally publishedYes

Scopus Subject Areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy

User-Defined Keywords

  • Experimental design
  • Multilayer feed forward network
  • Nonlinear calibration
  • Nonlinear fluorescence system
  • Uniform design (UD)


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