Abstract
Two immunologically distinct glycoproteins, with a molecular weight of 28,000 and 28,5000 respectively, were isolated from seeds of Luffa cylindrica using a procedure that involved acetone precipitation, gel filtration on Sephadex G-75 and ion exchange chromatography on CM-Sepharose CL-6B. The proteins differed in the content of aspartic acid, threonine, proline and alanine but were otherwise similar in amino acid composition. The proteins were capable of inducing mid-term abortion in mice, inhibiting protein synthesis in a cell-free system and suppressing thymidine uptake by human choriocarcinoma cells.
Original language | English |
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Pages (from-to) | 197-207 |
Number of pages | 11 |
Journal | Biochemistry International |
Volume | 27 |
Issue number | 2 |
Publication status | Published - 1992 |
Scopus Subject Areas
- Biochemistry