Two new prenylated isoflavones from Hedysarum multijugum

Wei Wang; Yu Ying Zhao; Hubiao CHEN; Qing Ying Zhang; Hong Liang

doi:10.1080/10286020.2016.1231672

Two new prenylated isoflavones from Hedysarum multijugum

Wei Wang, Yu Ying Zhao, Hubiao CHEN, Qing Ying Zhang, Hong Liang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Chemical investigation on the ethyl acetate extract of the roots of Hedysarum multijugum resulted in the isolation of two new prenylated isoflavonoids: 5, 7, 2′-trihydroxy-4′-methoxy-3′-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone A, 1) and 5, 7, 2′-trihydroxy-4′-methoxy-6, 8-di-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone B, 2). Their structures were elucidated on the basis of spectroscopic analyses, especially, ¹H and ¹³C NMR spectra in conjunction with their 2D experiments, ¹H-¹H COSY, HMQC, HMBC, and NOESY.

Original language	English
Pages (from-to)	444-447
Number of pages	4
Journal	Journal of Asian Natural Products Research
Volume	19
Issue number	5
DOIs	https://doi.org/10.1080/10286020.2016.1231672
Publication status	Published - 2017

Scopus Subject Areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

User-Defined Keywords

hedysarimisoflavone A
hedysarimisoflavone B
Hedysarum multijugum
isoflavones
Leguminosae

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10.1080/10286020.2016.1231672

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title = "Two new prenylated isoflavones from Hedysarum multijugum",

abstract = "Chemical investigation on the ethyl acetate extract of the roots of Hedysarum multijugum resulted in the isolation of two new prenylated isoflavonoids: 5, 7, 2′-trihydroxy-4′-methoxy-3′-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone A, 1) and 5, 7, 2′-trihydroxy-4′-methoxy-6, 8-di-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone B, 2). Their structures were elucidated on the basis of spectroscopic analyses, especially, 1H and 13C NMR spectra in conjunction with their 2D experiments, 1H-1H COSY, HMQC, HMBC, and NOESY.",

keywords = "hedysarimisoflavone A, hedysarimisoflavone B, Hedysarum multijugum, isoflavones, Leguminosae",

author = "Wei Wang and Zhao, {Yu Ying} and Hubiao CHEN and Zhang, {Qing Ying} and Hong Liang",

note = "Funding Information: This work was financially supported by the National Natural Science Foundation of China [number 20372002].",

year = "2017",

doi = "10.1080/10286020.2016.1231672",

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pages = "444--447",

journal = "Journal of Asian Natural Products Research",

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T1 - Two new prenylated isoflavones from Hedysarum multijugum

AU - Wang, Wei

AU - Zhao, Yu Ying

AU - CHEN, Hubiao

AU - Zhang, Qing Ying

AU - Liang, Hong

N1 - Funding Information: This work was financially supported by the National Natural Science Foundation of China [number 20372002].

PY - 2017

Y1 - 2017

N2 - Chemical investigation on the ethyl acetate extract of the roots of Hedysarum multijugum resulted in the isolation of two new prenylated isoflavonoids: 5, 7, 2′-trihydroxy-4′-methoxy-3′-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone A, 1) and 5, 7, 2′-trihydroxy-4′-methoxy-6, 8-di-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone B, 2). Their structures were elucidated on the basis of spectroscopic analyses, especially, 1H and 13C NMR spectra in conjunction with their 2D experiments, 1H-1H COSY, HMQC, HMBC, and NOESY.

AB - Chemical investigation on the ethyl acetate extract of the roots of Hedysarum multijugum resulted in the isolation of two new prenylated isoflavonoids: 5, 7, 2′-trihydroxy-4′-methoxy-3′-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone A, 1) and 5, 7, 2′-trihydroxy-4′-methoxy-6, 8-di-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone B, 2). Their structures were elucidated on the basis of spectroscopic analyses, especially, 1H and 13C NMR spectra in conjunction with their 2D experiments, 1H-1H COSY, HMQC, HMBC, and NOESY.

KW - hedysarimisoflavone A

KW - hedysarimisoflavone B

KW - Hedysarum multijugum

KW - isoflavones

KW - Leguminosae

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VL - 19

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JO - Journal of Asian Natural Products Research

JF - Journal of Asian Natural Products Research

SN - 1028-6020

IS - 5

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Two new prenylated isoflavones from Hedysarum multijugum

Abstract

Scopus Subject Areas

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