Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.

Zhen Yu Li, Hong Gui Xu, Zhongzhen ZHAO, Yue Wei Guo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Two new Daphniphyllum alkaloids, 4,21-deacetyl-deoxyyuzurimine (1) and macropodumine L (2), together with the two known related alkaloids, have been isolated from the bark of Daphniphyllum macropodum Miq. The structures of the new compounds were elucidated on the basis of the detailed analysis of spectroscopic data, chemical method, and by comparison of the spectroscopic data with those of known compounds. Compounds 2 and 4 exhibited weak cytotoxicity against human carcinoma cell lines SMMC-7721 and HO-8910.

Original languageEnglish
Pages (from-to)153-158
Number of pages6
JournalJournal of Asian Natural Products Research
Volume11
Issue number2
DOIs
Publication statusPublished - Feb 2009

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

User-Defined Keywords

  • Alkaloids
  • Cytotoxicity
  • Daphniphyllum macropodum Miq

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