Tunable chiral monophosphines as ligands in enantioselective rhodium-catalyzed ring-opening of oxabenzonorbornadienes with amines

Renshi Luo*, Ling Xie, Jianhua Liao, Hu Xin, Albert S.C. Chan

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

20 Citations (Scopus)

Abstract

A new tunable chiral monophosphine was used as a ligand for asymmetric rhodium-catalyzed ring-opening of oxabenzonorbornadiene with amines, providing a series of chiral ring-opened products in high yields (up to 97%) and with high enantioselectivities (>99%).The reaction can be performed at rt to obtain the desired product with high enantioselectivity.

Original languageEnglish
Pages (from-to)709-717
Number of pages9
JournalTetrahedron Asymmetry
Volume25
Issue number9
DOIs
Publication statusPublished - 15 May 2014

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