Tuber lectins with potentially exploitable bioactivities

Randy Chi Fai Cheung, Jack Ho Wong*, Tzi Bun Ng, Ryno Naude, Krzysztof Rolka, Ryan Tse, Tak Fu Tse, Helen Chan, Cho Wing SZE

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Lectins are a group of proteins or glycoproteins with various potentially exploitable bioactivities and have been capturing more interest recently. They have been isolated and reported from various tissues of a diversity of plant species. Tubers are modified and enlarged plant structures derived from stems or roots that are used for nutrient storage and asexual reproduction. A number of plants such as yam, taro and potato are grown for their edible tubers, and lectins are found to be one of the major storage proteins. These lectins exhibit potent bioactivities encompassing mitogenic, antitumor, antimicrobial, immunomodulatory, antioxidative, hypoglycemic, insecticidal and nematicidal activities. They are potential resources for development into functional or healthy foods and targets for food protein researchers.

Original languageEnglish
Pages (from-to)5986-6001
Number of pages16
JournalCurrent Medicinal Chemistry
Volume25
Issue number42
DOIs
Publication statusPublished - 2018

Scopus Subject Areas

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

User-Defined Keywords

  • Antimicrobial
  • Antioxidative
  • Antitumor
  • Hypoglycemic
  • Immunomodulatory
  • Insecticidal
  • Mitogenic
  • Nematicidal

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