Triterpene Glycosides from Cimicifuga racemosa

Yu Shao*, Amanda Harris, Mingfu Wang, Hongjie Zhang, Geoffrey A. Cordell, Mika Bowman, Ed Lemmo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

104 Citations (Scopus)

Abstract

Eight new triterpene glycosides named cimiracemosides A-H, respectively, and eight known triterpene glycosides were isolated from the rhizome extracts of black cohosh (Cimicifuga racemosa). The new compounds were determined by spectral data to be 21-hydroxycimigenol-3-O-α-L-arabinopyranoside (1), 21-hydroxycimigenol-3-O-β-D-xylopyranoside (2), cimigenol-3-O-α-L-arabinopyranoside (3), 12β-acetoxy-cimigenol-3-O-α-L-arabinopyranoside (4), 24-acetyhsodahurinol-3-O-β-D-xylopyranoside (5), 20(S),22(R),23(S),24(R)-16β:23:22:25-diepoxy-12β-acetoxy-3β,23 ,24-trihydroxy-19,19-cycloanost-7-ene-3-O-β-xylopyranoside (6), 20(S),22(R),23(S),24(R)-16β:23,22:25-diepoxy-12β-acetoxy-3β,23 ,24-trihydroxy-9,19-cycloanost-7-en-3-O-α-L-arabinopyranoside (7), and 20(S),22(R),23(S),24(R)-16β:23;22:25-diepoxy-12β-acetoxy-3β,23 ,24-trihydroxy-9,19-cycloanostane-3-O-β-D-xylopyranoside (8).

Original languageEnglish
Pages (from-to)905-910
Number of pages6
JournalJournal of Natural Products
Volume63
Issue number7
Early online date23 Jun 2000
DOIs
Publication statusPublished - 1 Jul 2000

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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