Translational research in nasopharyngeal carcinoma

Alan K.S. Chiang, Nai Ki MAK, Wai Tong Ng*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

10 Citations (Scopus)

Abstract

Nasopharyngeal carcinoma is well known to be a viral driven malignancy. Despite high loco-regional control rate with modern radiotherapy, distant metastasis remains as a major threat to the patients highlighting the importance of effective systemic therapy. Recent advances in the understanding of tumor biology, host cell-virus interaction and genetics have paved new ways for targeted therapies. This review summarizes the recent advances into our knowledge and understanding of NPC and highlights potential novel therapeutic strategies that may prove useful to treat this disease.

Original languageEnglish
Pages (from-to)345-352
Number of pages8
JournalOral Oncology
Volume50
Issue number5
DOIs
Publication statusPublished - May 2014

Scopus Subject Areas

  • Oral Surgery
  • Oncology
  • Cancer Research

User-Defined Keywords

  • Angiogenesis
  • EBV
  • Growth factor receptor
  • NPC
  • Targeted therapy

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