Towards selective DNA targeting: Synthesis of an antibody–macrocycle–intercalator conjugate

Timothy J. Norman; David Parker; Fiona C. Smith; David J. King

doi:10.1039/C39950001879

Towards selective DNA targeting: Synthesis of an antibody–macrocycle–intercalator conjugate

Timothy J. Norman, David Parker^*, Fiona C. Smith, David J. King

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

26 Citations (Scopus)

Abstract

The synthesis is reported of a trivalent conjugate incorporating a macrocyclic bifunctional complexing agent, an engineered human monoclonal antibody fragment and an established DNA intercalator.

Original language	English
Pages (from-to)	1879-1880
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	18
DOIs	https://doi.org/10.1039/C39950001879
Publication status	Published - Sept 1995

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@article{54933a50e1e445f998563aadb96ea7ee,

title = "Towards selective DNA targeting: Synthesis of an antibody–macrocycle–intercalator conjugate ",

abstract = "The synthesis is reported of a trivalent conjugate incorporating a macrocyclic bifunctional complexing agent, an engineered human monoclonal antibody fragment and an established DNA intercalator.",

author = "Norman, {Timothy J.} and David Parker and Smith, {Fiona C.} and King, {David J.}",

year = "1995",

month = sep,

doi = "10.1039/C39950001879",

language = "English",

pages = "1879--1880",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Royal Society of Chemistry",

number = "18",

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TY - JOUR

T1 - Towards selective DNA targeting

T2 - Synthesis of an antibody–macrocycle–intercalator conjugate

AU - Norman, Timothy J.

AU - Parker, David

AU - Smith, Fiona C.

AU - King, David J.

PY - 1995/9

Y1 - 1995/9

N2 - The synthesis is reported of a trivalent conjugate incorporating a macrocyclic bifunctional complexing agent, an engineered human monoclonal antibody fragment and an established DNA intercalator.

AB - The synthesis is reported of a trivalent conjugate incorporating a macrocyclic bifunctional complexing agent, an engineered human monoclonal antibody fragment and an established DNA intercalator.

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U2 - 10.1039/C39950001879

DO - 10.1039/C39950001879

M3 - Journal article

AN - SCOPUS:0029148454

SN - 0022-4936

SP - 1879

EP - 1880

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 18

ER -

Towards selective DNA targeting: Synthesis of an antibody–macrocycle–intercalator conjugate

Abstract

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