Total synthesis of the L-hexoses

  • Soo Y. Ko*
  • , Albert W M LEE
  • , Satoru Masamune
  • , Lawrence A. Reed
  • , K. Barry Sharpless
  • , Frederick J. Walker
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

195 Citations (Scopus)

Abstract

Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four steps. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.

Original languageEnglish
Pages (from-to)949-951
Number of pages3
JournalScience
Volume220
Issue number4600
DOIs
Publication statusPublished - 1983

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