Three New Ent-Kauranoids from Isodon Phyllostachys

Xian Li*, Jianxin Pu, Shenghong Li, Shengxiong Huang, Zhiying Weng, Quanbin Han, Handong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

5 Citations (Scopus)


Three new ent-kaurane diterpenoids, phyllostacins C-E (1-3), together with six known analogues, oridonin (4), ponicidin (5), effusanin A (6), rabdoternin E (7), rabdoternin F (8), and macrocalyxoformin E (9), were isolated from the aerial parts of Isodon phyllostachys. The structures of compounds (1-3) were determined on the basis of spectroscopic methods including extensive 1D and 2D NMR analysis. All compounds were evaluated for their inhibitory activity against K562, HL60 and HepG2 (hepatoma) cell lines.

Original languageEnglish
Pages (from-to)2441-2447
Number of pages7
Issue number11
Early online date8 Aug 2007
Publication statusPublished - 1 Nov 2007

Scopus Subject Areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

User-Defined Keywords

  • Biological Activity
  • Diterpenoid
  • ent-Kaurane
  • Isodon phyllostachys
  • Phyllostacins C-E


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