The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use

  • Filip Kielar
  • , Ga Lai Law
  • , Elizabeth J. New
  • , David Parker*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

65 Citations (Scopus)

Abstract

Introduction of different substituents at the 7-position of a sensitising azaxanthone group in a series of emissive Eu and Tb complexes can determine the intracellular uptake and distribution profile and may be linked to modulation of protein affinity.

Original languageEnglish
Pages (from-to)2256-2258
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume6
Issue number13
DOIs
Publication statusPublished - 16 May 2008

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