Keyphrases
Apoptosis-inducing Activity
100%
Dioscin
100%
Human Leukemia Cell Line
100%
Diosgenyl Saponin
100%
Apoptosis
80%
Multinucleation
60%
Mechanism of Action
20%
Cytotoxicity
20%
M Phase
20%
Caspase-8
20%
Caspase-9
20%
Mitochondrial Pathway
20%
Mitotic Arrest
20%
Hydrolysate
20%
Diosgenin
20%
Steroidal Saponins
20%
Chronic Myeloid Leukemia
20%
Antiproliferative Activity
20%
K562 Cells
20%
Anti-apoptotic Bcl-2
20%
K562 Leukemia Cells
20%
Phosphatidylserine Externalization
20%
Biological Function
20%
HL-60 Cells
20%
Flow Cytometric Analysis
20%
Enlargement
20%
Apoptotic Pathway
20%
Effects on Humans
20%
K562
20%
Cell Volume
20%
Human Leukemia HL-60 Cells
20%
Antimitotic Agents
20%
Hypodiploidy
20%
Wright-Giemsa Staining
20%
Myeloblasts
20%
Sapogenin
20%
NB4 Cells
20%
Cytomorphology
20%
Human Promyelocytic Leukemia
20%
Trillin
20%
Biochemistry, Genetics and Molecular Biology
Programmed Cell Death
100%
Saponin
100%
K562 Cells
40%
Mitochondrion
20%
Flow Cytometry
20%
Cytotoxicity
20%
Mitosis Inhibition
20%
Diosgenin
20%
Antiproliferative Activity
20%
Phosphatidylserine
20%
Bcl-2
20%
Downregulation
20%
Biological Functions
20%
DAPI
20%
Mitosis
20%
Caspase 8
20%
Cell Cycle M Phase
20%
Caspase-9
20%
Cell Volume
20%
Giemsa Stain
20%
Myeloblast
20%
Pharmacology, Toxicology and Pharmaceutical Science
Leukemia
100%
Saponin
100%
Cytotoxicity
25%
Flow Cytometry
25%
Caspase 9
25%
Caspase 8
25%
Phosphatidylserine
25%
Sapogenin
25%
Chronic Myeloid Leukemia
25%
Antiapoptotic
25%
Diosgenin
25%
4',6 Diamidino 2 Phenylindole
25%
Protein Bcl 2
25%
Promyelocytic Leukemia
25%
Antimitotic Agent
25%