The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

P. L. Lam; K. K.H. Lee; Y. W. Ho; R. S.M. Wong; S. W. Tong; C. H. Cheng; K. H. Lam; J. C.O. Tang; Zhaoxiang BIAN; R. Gambari; S. H.L. Kok; Chung Hin CHUI

doi:10.1039/c4ra00195h

The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

P. L. Lam, K. K.H. Lee, Y. W. Ho, R. S.M. Wong, S. W. Tong, C. H. Cheng, K. H. Lam, J. C.O. Tang, Zhaoxiang BIAN, R. Gambari^*, S. H.L. Kok, Chung Hin CHUI

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

9 Citations (Scopus)

Abstract

This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.

Original language	English
Pages (from-to)	14109-14114
Number of pages	6
Journal	RSC Advances
Volume	4
Issue number	27
DOIs	https://doi.org/10.1039/c4ra00195h
Publication status	Published - 2014

Scopus Subject Areas

Chemistry(all)
Chemical Engineering(all)

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c4ra00195h

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@article{a6517c5dbc2b46709fd95f1b2bc26950,

title = "The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin",

abstract = "This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.",

author = "Lam, {P. L.} and Lee, {K. K.H.} and Ho, {Y. W.} and Wong, {R. S.M.} and Tong, {S. W.} and Cheng, {C. H.} and Lam, {K. H.} and Tang, {J. C.O.} and Zhaoxiang BIAN and R. Gambari and Kok, {S. H.L.} and CHUI, {Chung Hin}",

year = "2014",

doi = "10.1039/c4ra00195h",

language = "English",

volume = "4",

pages = "14109--14114",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "27",

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TY - JOUR

T1 - The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

AU - Lam, P. L.

AU - Lee, K. K.H.

AU - Ho, Y. W.

AU - Wong, R. S.M.

AU - Tong, S. W.

AU - Cheng, C. H.

AU - Lam, K. H.

AU - Tang, J. C.O.

AU - BIAN, Zhaoxiang

AU - Gambari, R.

AU - Kok, S. H.L.

AU - CHUI, Chung Hin

PY - 2014

Y1 - 2014

N2 - This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.

AB - This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.

UR - http://www.scopus.com/inward/record.url?scp=84896913672&partnerID=8YFLogxK

U2 - 10.1039/c4ra00195h

DO - 10.1039/c4ra00195h

M3 - Journal article

AN - SCOPUS:84896913672

SN - 2046-2069

VL - 4

SP - 14109

EP - 14114

JO - RSC Advances

JF - RSC Advances

IS - 27

ER -

The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

Abstract

Scopus Subject Areas

UN SDGs

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