The development of chitosan based microcapsules as delivery vehicles for orally administered daunorubicin

P. L. Lam, K. K.H. Lee, Y. W. Ho, R. S.M. Wong, S. W. Tong, C. H. Cheng, K. H. Lam, J. C.O. Tang, Zhaoxiang BIAN, R. Gambari*, S. H.L. Kok, Chung Hin CHUI

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

This study reports the use of chitosan microcapsules for daunorubicin delivery via an oral route. The potential oral delivery of the daunorubicin/chitosan microcapsules was examined using an in vivo athymic nude mice xenograft model with Non-Hodgkin's lymphoma cells. Microencapsulated daunorubicin could be administered orally with tumour growth inhibition activity.

Original languageEnglish
Pages (from-to)14109-14114
Number of pages6
JournalRSC Advances
Volume4
Issue number27
DOIs
Publication statusPublished - 2014

Scopus Subject Areas

  • Chemistry(all)
  • Chemical Engineering(all)

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