TY - JOUR
T1 - The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity
AU - Zhao, Yueshui
AU - Chen, Bo
AU - Shen, Jing
AU - Wan, Lin
AU - Zhu, Yinxin
AU - Yi, Tao
AU - Xiao, Zhangang
N1 - Funding Information:
This study is supported by grants from the National Natural Science Foundation of China (Grant nos. 81503093, 81602166, and 81672444) and the Natural Science Foundation of Jiangsu Province (BK2014086).
PY - 2017
Y1 - 2017
N2 - Over the past two decades, obesity has been one of the major public health concerns in most countries. In the search for new molecules that could be used for the treatment of obesity, good perspectives have been opened up for polyphenols, a class of natural bioactive phytochemicals. Experimental and limited clinical trial evidence supports that some polyphenols such as quercetin, curcumin, and resveratrol have potential benefit functions on obesity treatment. This brief review focuses on the main functions of the above-named polyphenols on adipose tissue. These polyphenols may play beneficial effects on adipose tissue under obese condition by alleviating intracellular oxidative stress, reducing chronic low-grade inflammation, inhibiting adipogenesis and lipogenesis, and suppressing the differentiation of preadipocytes to mature adipocytes.
AB - Over the past two decades, obesity has been one of the major public health concerns in most countries. In the search for new molecules that could be used for the treatment of obesity, good perspectives have been opened up for polyphenols, a class of natural bioactive phytochemicals. Experimental and limited clinical trial evidence supports that some polyphenols such as quercetin, curcumin, and resveratrol have potential benefit functions on obesity treatment. This brief review focuses on the main functions of the above-named polyphenols on adipose tissue. These polyphenols may play beneficial effects on adipose tissue under obese condition by alleviating intracellular oxidative stress, reducing chronic low-grade inflammation, inhibiting adipogenesis and lipogenesis, and suppressing the differentiation of preadipocytes to mature adipocytes.
UR - http://www.scopus.com/inward/record.url?scp=85029187639&partnerID=8YFLogxK
U2 - 10.1155/2017/1459497
DO - 10.1155/2017/1459497
M3 - Review article
C2 - 29138673
AN - SCOPUS:85029187639
SN - 1942-0900
VL - 2017
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 1459497
ER -