Tests of noninferiority via rate difference for three-arm clinical trials with placebo

Keyphrases

• Clinical Trials 100%
• Placebo 100%
• Rate Difference 100%
• Non-inferiority 100%
• Maximum Likelihood Estimation Method 66%
• Restricted Maximum Likelihood 66%
• Simulation Study 33%
• Type I Error Rate 33%
• Estimation Method 33%
• Sampling Methods 33%
• Drug Treatment 33%
• Statistical Methods 33%
• Nominal Level 33%
• Placebo-controlled 33%
• Placebo Groups 33%
• Active Control 33%
• Pharmacological Studies 33%
• Real Examples 33%
• Binary Outcome 33%
• Outcome-based 33%
• Non-inferiority Trial 33%
• Internal Validation 33%
• Control Reference 33%
• Patients with Functional Dyspepsia 33%
• Acute Migraine 33%
• Sample Size Allocation 33%
• Sample-based Estimation 33%
• Experimental Drugs 33%

Mathematics

• Estimation Method 100%
• Maximum Likelihood 66%
• Simulation Study 33%
• Closed Form 33%
• Error Rate 33%
• Test Procedure 33%
• Asymptotics 33%
• Statistical Method 33%
• Method Performs 33%
• Nominal Level 33%
• Placebo Group 33%
• Actual Type 33%