Abstract
In this study, a detailed mapping of stanniocalcin (STC) mRNA was conducted at various developmental stages of male and female mouse brains. The developmental profile of STC expression in mouse brains indicated that the transcripts were detectable on E12 and peaked on E16, and days 1 and 2 of postnatal stages and then declined slowly. There was no observable difference in the descending trends of STC expression in both male and female mouse brains at different postnatal periods (3, 5, 7, 9 and 11 weeks). As concerns the spatial distribution, the results indicated a differential expression of STC in the various regions of the brain; the highest level was detected in the striatum, followed by the hippocampus, parietal cortex, hypothalamus, frontal cortex, cerebellum and brain stem. Similar patterns of expression were observed in the mature rat brain. Our findings lend further support to the notion that STC is involved in distinct neural functions.
| Original language | English |
|---|---|
| Pages (from-to) | 139-142 |
| Number of pages | 4 |
| Journal | Neuroembryology |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 2004 |
Scopus Subject Areas
- Neuroscience(all)
- Embryology
- Developmental Neuroscience
- Developmental Biology
User-Defined Keywords
- Hippocampus
- Northern blot
- STC
- Striatum