Templated Synthesis of Interlocked Molecules

Fabio Aricó, Jovica D. Badjic, Stuart J. Cantrill, Amar H. Flood, Ken C.F. Leung, Yi Liu, J. Fraser Stoddart*

*Corresponding author for this work

Research output: Chapter in book/report/conference proceedingChapterpeer-review

163 Citations (Scopus)

Abstract

Mechanically interlocked molecular compounds can be synthesized in high yields by using template-directed assistance to covalent synthesis. Catenanes and rotaxanes are two classes of mechanically interlocked molecules that have been prepared using a variety of methods such as "clipping", "slipping", and "threading-followed-by-stoppering", under both kinetic and thermodynamic regimes. These different methods have utilized a range of templates such as transistion metals, π-donor/π-acceptors, and hydrogen-bonding motifs. Multivalency has emerged as another tool to aid and abet the supramolecularly assisted synthesis of mechanically interlocked molecules. Recent advances in our understanding of the nature of the mechanical bond has led to the construction of molecular machines with controllable motions that have, in one instance, been introduced into molecular electronic devices.

Original languageEnglish
Title of host publicationTemplates in Chemistry II
EditorsChristoph A Schalley, Fritz Vögtle, Karl Heinz Dötz
PublisherSpringer
Pages203-259
Number of pages57
Edition1st
ISBN (Electronic)9783540314714
ISBN (Print)9783642062018, 9783540230878
DOIs
Publication statusPublished - 15 Jun 2005

Publication series

NameTopics in Current Chemistry
Volume249
ISSN (Print)0340-1022
ISSN (Electronic)1436-5049

Scopus Subject Areas

  • Chemistry(all)

User-Defined Keywords

  • Catenanes
  • Dynamic chemistry
  • Molecular machines
  • Multivalency
  • Rotaxanes

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