Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET

Hongyi Hou; Ken C F LEUNG; Daniela Lanari; Alshakim Nelson; J. Fraser Stoddart; Robert H. Grubbs

doi:10.1021/ja065572j

Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET

Hongyi Hou, Ken C F LEUNG, Daniela Lanari, Alshakim Nelson, J. Fraser Stoddart, Robert H. Grubbs

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

46 Citations (Scopus)

Abstract

A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium−alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.

Original language	English
Pages (from-to)	15358-15359
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	128
Issue number	48
DOIs	https://doi.org/10.1021/ja065572j
Publication status	Published - 6 Dec 2006

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title = "Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET",

abstract = "A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium−alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.",

author = "Hongyi Hou and LEUNG, {Ken C F} and Daniela Lanari and Alshakim Nelson and Stoddart, {J. Fraser} and Grubbs, {Robert H.}",

note = "We thank the office of Naval Research (ONR) for supporting this research through the Multidisciplinary University Research Initiative (MURI) program. ",

year = "2006",

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doi = "10.1021/ja065572j",

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T1 - Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET

AU - Hou, Hongyi

AU - LEUNG, Ken C F

AU - Lanari, Daniela

AU - Nelson, Alshakim

AU - Stoddart, J. Fraser

AU - Grubbs, Robert H.

N1 - We thank the office of Naval Research (ONR) for supporting this research through the Multidisciplinary University Research Initiative (MURI) program.

PY - 2006/12/6

Y1 - 2006/12/6

N2 - A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium−alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.

AB - A trifurcated template, containing three secondary dialkylammonium ion recognition sites for encirclement by a dibenzo [24]crown-8-containing acyclic diene, is used to promote acyclic diene metatheses (ADMET) catalyzed by ruthenium−alkylidene complexes, affording a cyclic trimer in 55% yield. Following this one-step, threefold ADMET reaction, the resulting cyclic trimer was isolated by preparative HPLC and characterized by NMR spectroscopy and mass spectrometry.

U2 - 10.1021/ja065572j

DO - 10.1021/ja065572j

M3 - Journal article

SN - 0002-7863

VL - 128

SP - 15358

EP - 15359

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 48

ER -

Template-Directed One-Step Synthesis of Cyclic Trimers by ADMET

Abstract

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