TY - JOUR
T1 - Targeted and non-targeted analyses reveal trophic biomagnification of rubber-derived chemicals in an estuarine food web near China's largest rubber production region
AU - Liu, Yuan
AU - Zhou, Jia-Ming
AU - Wu, Nian-Nian
AU - Liu, Shan
AU - Liao, Xiao-Liang
AU - Wu, Haijiang
AU - Zhu, Lin
AU - Li, Heng-Xiang
AU - Lin, Lang
AU - Hou, Rui
AU - Li, Zhi-Hua
AU - Xu, Xiang-Rong
AU - Chen, Zhi-Feng
AU - Cai, Zongwei
N1 - The authors would like to acknowledge the support by fund of the National Natural Science Foundation of China (Nos. 42177388, U21A2036, and 42177254), Hainan Province Science and Technology Special Fund (No. ZDYF2022SHFZ317), Science and Technology Innovation Special Project of Sanya City (No. 2022KJCX74), the Science and Technology Program of Guangzhou, China (2024A04J2991).
Publisher Copyright:
© 2025 Elsevier B.V.
PY - 2025/6/15
Y1 - 2025/6/15
N2 - The emergence of rubber-derived chemicals (RDCs) has garnered significant environmental attention, particularly N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q) linked to acute mortality in salmonids. However, the trophic transfer of RDCs within marine ecosystems is notably sparse. Here, we investigated RDCs in the Nandu River estuary near China's largest rubber production region through an integrated targeted and non-targeted approach. Twelve targeted and 28 non-targeted RDCs were identified in biological samples. For targeted RDCs, total mean concentrations (ng/g, wet weight) showed a descending order of crab (702) > shellfish (531) > snail (491) > shrimp (392) > cuttlefish (342) > fish (190), while those for non-targeted RDCs followed the order of fish (3.91 ×103) > shellfish (3.08 ×103) > cuttlefish (2.96 ×103) > shrimp (2.78 ×103) > snail (1.61 ×103) > crab (1.36 ×103). Thirteen RDCs exhibited biomagnification potential with trophic magnification factors (TMFs) of 1.05–3.24, while nine compounds displayed biodilution trends (TMFs: 0.56–0.93). Organism-water partition coefficients, derived from multi-parameter linear free-energy relationships, more accurately elucidate biomagnification mechanisms of RDCs. Furthermore, 60 % of RDCs exhibited persistence, bioaccumulation and toxicity properties. This research underscores the importance of integrating targeted and non-targeted approaches of RDCs in biomonitoring, offering a more comprehensive view of cumulative chemical risks to humans and wildlife.
AB - The emergence of rubber-derived chemicals (RDCs) has garnered significant environmental attention, particularly N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q) linked to acute mortality in salmonids. However, the trophic transfer of RDCs within marine ecosystems is notably sparse. Here, we investigated RDCs in the Nandu River estuary near China's largest rubber production region through an integrated targeted and non-targeted approach. Twelve targeted and 28 non-targeted RDCs were identified in biological samples. For targeted RDCs, total mean concentrations (ng/g, wet weight) showed a descending order of crab (702) > shellfish (531) > snail (491) > shrimp (392) > cuttlefish (342) > fish (190), while those for non-targeted RDCs followed the order of fish (3.91 ×103) > shellfish (3.08 ×103) > cuttlefish (2.96 ×103) > shrimp (2.78 ×103) > snail (1.61 ×103) > crab (1.36 ×103). Thirteen RDCs exhibited biomagnification potential with trophic magnification factors (TMFs) of 1.05–3.24, while nine compounds displayed biodilution trends (TMFs: 0.56–0.93). Organism-water partition coefficients, derived from multi-parameter linear free-energy relationships, more accurately elucidate biomagnification mechanisms of RDCs. Furthermore, 60 % of RDCs exhibited persistence, bioaccumulation and toxicity properties. This research underscores the importance of integrating targeted and non-targeted approaches of RDCs in biomonitoring, offering a more comprehensive view of cumulative chemical risks to humans and wildlife.
KW - Bioaccumulation
KW - Biomagnification mechanisms
KW - Marine ecosystem
KW - Non-targeted screening
KW - Rubber-derived chemicals
UR - http://www.scopus.com/inward/record.url?scp=105008206284&partnerID=8YFLogxK
U2 - 10.1016/j.jhazmat.2025.138958
DO - 10.1016/j.jhazmat.2025.138958
M3 - Journal article
SN - 0304-3894
VL - 495
JO - Journal of Hazardous Materials
JF - Journal of Hazardous Materials
M1 - 138958
ER -
