Synthesis of the central C18–C30 core of the phorboxazole natural products

  • Chi Sing Lee
  • , Craig J. Forsyth*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

62 Citations (Scopus)

Abstract

A direct synthesis of the central C18-C30 core of the phorboxazole natural products has been developed. This involves construction of an acyclic acrylate using Paterson's (E)-enol borinate aldol methodology followed by an intramolecular hetero-Michael addition to form the central pyran ring of the natural products.

Original languageEnglish
Pages (from-to)6449-6452
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number36
DOIs
Publication statusPublished - 2 Sept 1996

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