Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA

Zhi Xue; Daniel W J KWONG; Ling Wei Xue; Qing Liu; An Xin Hou; Rick W K WONG

doi:10.1002/cbdv.200800182

Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA

Zhi Xue, Daniel W J KWONG, Ling Wei Xue, Qing Liu, An Xin Hou^*, Rick W K WONG

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

6 Citations (Scopus)

Abstract

Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by ¹H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies. The relative rates of singlet-oxygen production from the diselenide-linked porphyrin dimers upon photoirradiation were also measured.

Original language	English
Pages (from-to)	1131-1143
Number of pages	13
Journal	Chemistry and Biodiversity
Volume	6
Issue number	7
DOIs	https://doi.org/10.1002/cbdv.200800182
Publication status	Published - Jul 2009

Scopus Subject Areas

Bioengineering
Biochemistry
Chemistry(all)
Molecular Medicine
Molecular Biology

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10.1002/cbdv.200800182

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title = "Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA",

abstract = "Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by 1H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies. The relative rates of singlet-oxygen production from the diselenide-linked porphyrin dimers upon photoirradiation were also measured.",

author = "Zhi Xue and KWONG, {Daniel W J} and Xue, {Ling Wei} and Qing Liu and Hou, {An Xin} and WONG, {Rick W K}",

year = "2009",

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doi = "10.1002/cbdv.200800182",

language = "English",

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T1 - Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA

AU - Xue, Zhi

AU - KWONG, Daniel W J

AU - Xue, Ling Wei

AU - Liu, Qing

AU - Hou, An Xin

AU - WONG, Rick W K

PY - 2009/7

Y1 - 2009/7

N2 - Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by 1H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies. The relative rates of singlet-oxygen production from the diselenide-linked porphyrin dimers upon photoirradiation were also measured.

AB - Novel diselenide-linked porphyrin dimers were synthesized under phase-transfer catalysis conditions. The targeted compounds were characterized by 1H-NMR, high-resolution mass spectrometry, UV/VIS and fluorescence spectroscopies, redox-potential measurements, and elemental analysis. The interaction of the title compounds with DNA was studied using UV/VIS, fluorescence, and circular dichroism (CD) spectroscopies. The relative rates of singlet-oxygen production from the diselenide-linked porphyrin dimers upon photoirradiation were also measured.

UR - http://www.scopus.com/inward/record.url?scp=67749095057&partnerID=8YFLogxK

U2 - 10.1002/cbdv.200800182

DO - 10.1002/cbdv.200800182

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SN - 1612-1872

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EP - 1143

JO - Chemistry and Biodiversity

JF - Chemistry and Biodiversity

IS - 7

ER -

Synthesis of novel diselenide-linked porphyrin dimers under phase-transfer catalysis condition and their interactions with DNA

Abstract

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