Synthesis of New Macrocyclic Amino-Phosphinic Acid Complexing Agents and Their C-and P-Functionalised Derivatives for Protein Linkage

C. J. Broan*, E. Cole, K. J. Jankowski, D. Parker, K. Pulukkody, B. A. Boyce, N. R.A. Beeley, K. Millar, A. T. Millican

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

50 Citations (Scopus)

Abstract

The synthesis of various macrocyclic complexing agents with alkyl- and arylphosphinic substituents is reported together with their C- and N-functionalised analogues as active esters suitable for antibody conjugation.

Original languageEnglish
Pages (from-to)63-68
Number of pages6
JournalSynthesis
Issue number1-2
DOIs
Publication statusPublished - Jan 1992

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