Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols

Xiaoxiang Zhang*, Wan Teng Teo, Weidong Rao, Edmond Dik Lung MA, Chung Hang Leung, Philip Wai Hong Chan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

An efficient synthetic method to prepare highly substituted indenes in moderate to excellent yields that relies on Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols under mild conditions is described.

Original languageEnglish
Pages (from-to)3881-3884
Number of pages4
JournalTetrahedron Letters
Volume55
Issue number29
DOIs
Publication statusPublished - 16 Jul 2014

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

User-Defined Keywords

  • Brønsted acid
  • Friedel-Crafts reaction
  • Homoallylic alcohols
  • Homogeneous catalysis
  • Indene derivatives

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