Synthesis of charged and uncharged complexes of gadolinium and yttrium with cyclic polyazaphosphinic acid ligands for in vivo applications

Keyphrases

• Gadolinium 100%
• Neutral Complexes 100%
• In Vivo Applications 100%
• Yttrium 100%
• Dissociation 50%
• Lipophilicity 50%
• Carboxylic Acid Groups 50%
• Carboxylate 50%
• PH Range 50%
• 1H{31P} 50%
• NMR Spectroscopy 50%
• Gadolinium Complex 50%
• 1,4,7,10-tetraazacyclododecane 50%
• Cationic Complexes 50%
• Selective Functionalization 50%
• Anionic Complexes 50%
• Complexing Agent 50%
• Phosphinate Complexes 50%
• Phosphinic Acid 50%
• 153Gd 50%
• Diamagnetic Complexes 50%

Chemistry

• Gadolinium 100%
• Yttrium 100%
• Carboxylic Acid 66%
• Lipophilicity 33%
• Phosphorus-31 Magnetic Resonance Spectroscopy 33%
• 1H NMR Spectroscopy 33%
• Phosphinate 33%
• 1,4,7,10-tetraazacyclododecane 33%
• Diamagnetic 33%
• Phosphinic Acid 33%
• 89Y NMR Spectroscopy 33%