TY - JOUR
T1 - Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water
AU - Xia, Jun
AU - Qiu, Renhua
AU - Yin, Shuangfeng
AU - Zhang, Xiaowen
AU - Luo, Shenglian
AU - Au, Chak Tong
AU - Xia, Kai
AU - Wong, Wai Yeung
N1 - Funding Information:
This work was financially supported by the NSFC (Grant Nos. 20973056 , 20873038 and J0830415 ), the National 863 Program of China ( 2009AA05Z319 ), and the Outstanding Young Research Award of NSFC (Grant No. E50725825 ). C.T. Au thanks the HNU for an adjunct professorship.
PY - 2010/5/15
Y1 - 2010/5/15
N2 - An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of β-amino ketones.
AB - An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of β-amino ketones.
KW - Catalyst
KW - Diastereoselectivity
KW - Direct Mannich reaction
KW - Lewis acid
KW - Organoantimony
UR - http://www.scopus.com/inward/record.url?scp=77953290268&partnerID=8YFLogxK
U2 - 10.1016/j.jorganchem.2010.03.003
DO - 10.1016/j.jorganchem.2010.03.003
M3 - Journal article
AN - SCOPUS:77953290268
SN - 0022-328X
VL - 695
SP - 1487
EP - 1492
JO - Journal of Organometallic Chemistry
JF - Journal of Organometallic Chemistry
IS - 10-11
ER -