TY - JOUR
T1 - Synthesis and binding properties of amide-functionalised polyaza macrocycles
AU - Kataky, Ritu
AU - Matthes, Karen E.
AU - Nicholson, Patrick E.
AU - Parker, David
AU - Buschmann, Hans J.
PY - 1990/8
Y1 - 1990/8
N2 - A series of amide N-functionalised coronands has been prepared based on parent [9]-N3, [12]-N3, [12]-N2O2, and [12]-N4 polyazamacrocycles. Complexation with alkali and alkaline earth cations, particularly Li+, Na+, and Ca 2+, has been monitored by using 13C NMR and IR spectroscopy, fast atom bombardment mass spectrometry, calorimetric, and potentiometric analysis in aqueous and alcoholic media. Particularly strong complexation in water has been observed for Ca2+ with 1,4,7,10-tetrakis(N,N-dimethylacetamido)-1,4,7,10-tetra-azacyclododecane, (9) (log Ks = 6.82-[H2O, 298 K]), and selective Ca 2+ complexation was observed with 1,7-dioxa-4,10- bis(dimethylethanamido)-4,10-diazacyclododecane, (7).
AB - A series of amide N-functionalised coronands has been prepared based on parent [9]-N3, [12]-N3, [12]-N2O2, and [12]-N4 polyazamacrocycles. Complexation with alkali and alkaline earth cations, particularly Li+, Na+, and Ca 2+, has been monitored by using 13C NMR and IR spectroscopy, fast atom bombardment mass spectrometry, calorimetric, and potentiometric analysis in aqueous and alcoholic media. Particularly strong complexation in water has been observed for Ca2+ with 1,4,7,10-tetrakis(N,N-dimethylacetamido)-1,4,7,10-tetra-azacyclododecane, (9) (log Ks = 6.82-[H2O, 298 K]), and selective Ca 2+ complexation was observed with 1,7-dioxa-4,10- bis(dimethylethanamido)-4,10-diazacyclododecane, (7).
UR - http://www.scopus.com/inward/record.url?scp=37049073209&partnerID=8YFLogxK
U2 - 10.1039/p29900001425
DO - 10.1039/p29900001425
M3 - Journal article
AN - SCOPUS:37049073209
SN - 1472-779X
SP - 1425
EP - 1432
JO - Journal of the Chemical Society, Perkin Transactions 2
JF - Journal of the Chemical Society, Perkin Transactions 2
IS - 8
ER -
