TY - JOUR
T1 - Surface-enhanced laser desorption/ionization mass spectrometry for rapid analysis of organic environmental pollutants by using polydopamine nanospheres as a substrate
AU - Luo, Kailong
AU - Yang, Baichuan
AU - Guo, Wenjing
AU - Sun, Qianqian
AU - Dan, Ouyang
AU - Lin, Zian
AU - CAI, Zongwei
N1 - Funding Information:
Thanks to the National Natural Science Foundation of China (91843301, 21974021, and 21675025) and the Natural Science Foundation of Fujian Province (2018J01683) for funding.
PY - 2020/8/21
Y1 - 2020/8/21
N2 - Polydopamine nanospheres (PDA) were designed to serve as a new substrate for surface-enhanced desorption/ionization mass spectrometry (SELDI-MS). Compared with conventional organic matrices, the PDA substrate showed superior LDI performance for analyzing a wide variety of environmental pollutants, including polycyclic aromatic hydrocarbons, bisphenols, benzophenones, sulfonamides, perfluorinated compounds and estrogens. Benzoapyrene was used to evaluate the ability of quantitative analysis and its corresponding limit of detection (LOD) of as low as 0.1 ng was achieved. High sensitivity and good reproducibility of PDA-based SELDI-MS allowed us to determine ultratrace PAHs in airborne particulate matters (PM2.5), and the corresponding concentration of BaP in different PM2.5 were 5.32, 8.97 and 9.79 ng m-3. Significantly, PDA exhibits the characteristics of simple synthesis, low cost, non-toxicity and less matrix interference, which provides the possibility for the sensitive analysis of organic small molecule pollutants at low concentrations in complex environmental samples. This journal is
AB - Polydopamine nanospheres (PDA) were designed to serve as a new substrate for surface-enhanced desorption/ionization mass spectrometry (SELDI-MS). Compared with conventional organic matrices, the PDA substrate showed superior LDI performance for analyzing a wide variety of environmental pollutants, including polycyclic aromatic hydrocarbons, bisphenols, benzophenones, sulfonamides, perfluorinated compounds and estrogens. Benzoapyrene was used to evaluate the ability of quantitative analysis and its corresponding limit of detection (LOD) of as low as 0.1 ng was achieved. High sensitivity and good reproducibility of PDA-based SELDI-MS allowed us to determine ultratrace PAHs in airborne particulate matters (PM2.5), and the corresponding concentration of BaP in different PM2.5 were 5.32, 8.97 and 9.79 ng m-3. Significantly, PDA exhibits the characteristics of simple synthesis, low cost, non-toxicity and less matrix interference, which provides the possibility for the sensitive analysis of organic small molecule pollutants at low concentrations in complex environmental samples. This journal is
UR - http://www.scopus.com/inward/record.url?scp=85089359082&partnerID=8YFLogxK
U2 - 10.1039/d0an00895h
DO - 10.1039/d0an00895h
M3 - Journal article
C2 - 32643716
AN - SCOPUS:85089359082
SN - 0003-2654
VL - 145
SP - 5664
EP - 5669
JO - Analyst
JF - Analyst
IS - 16
ER -