Sulfonyl hydrazine as new functionality in organocatalysis: Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition

Ling Yan Chen, Hao He, Bao Jian Pei, Wing Hong CHAN, Albert W M LEE

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Sulfonyl hydrazine is a new functionality for the Lewis base organocatalysis. Nα-substituted camphorsulfonyl hydrazines (CaSH) are effective organocatalysts for the asymmetric aza-Michael addition to α,β-unsaturated aldehydes with enantioselectivity of up to 90%.

Original languageEnglish
Article numberC00609SS
Pages (from-to)1573-1577
Number of pages5
JournalSynthesis
Issue number9
DOIs
Publication statusPublished - May 2009

Scopus Subject Areas

  • Catalysis
  • Organic Chemistry

User-Defined Keywords

  • α,β-unsaturated aldehyde
  • Aza-Michael addition
  • Camphorsulfonyl hydrazine
  • Organocatalysis
  • Sulfonyl hydrazine

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