Sulfonyl hydrazine as new functionality in organocatalysis: Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition

Ling Yan Chen; Hao He; Bao Jian Pei; Wing Hong Chan; Albert W.M. Lee

doi:10.1055/s-0029-1216639

Sulfonyl hydrazine as new functionality in organocatalysis: Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition

Ling Yan Chen, Hao He, Bao Jian Pei, Wing Hong Chan, Albert W.M. Lee

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

25 Citations (Scopus)

Abstract

Sulfonyl hydrazine is a new functionality for the Lewis base organocatalysis. N^α-substituted camphorsulfonyl hydrazines (CaSH) are effective organocatalysts for the asymmetric aza-Michael addition to α,β-unsaturated aldehydes with enantioselectivity of up to 90%.

Original language	English
Article number	C00609SS
Pages (from-to)	1573-1577
Number of pages	5
Journal	Synthesis
Issue number	9
DOIs	https://doi.org/10.1055/s-0029-1216639
Publication status	Published - May 2009

Scopus Subject Areas

Catalysis
Organic Chemistry

User-Defined Keywords

α,β-unsaturated aldehyde
Aza-Michael addition
Camphorsulfonyl hydrazine
Organocatalysis
Sulfonyl hydrazine

Access to Document

10.1055/s-0029-1216639

Cite this

@article{7197acb18d184357969ebcd6a8389921,

title = "Sulfonyl hydrazine as new functionality in organocatalysis: Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition",

abstract = "Sulfonyl hydrazine is a new functionality for the Lewis base organocatalysis. Nα-substituted camphorsulfonyl hydrazines (CaSH) are effective organocatalysts for the asymmetric aza-Michael addition to α,β-unsaturated aldehydes with enantioselectivity of up to 90%.",

keywords = "α,β-unsaturated aldehyde, Aza-Michael addition, Camphorsulfonyl hydrazine, Organocatalysis, Sulfonyl hydrazine",

author = "Chen, {Ling Yan} and Hao He and Pei, {Bao Jian} and Chan, {Wing Hong} and Lee, {Albert W.M.}",

year = "2009",

month = may,

doi = "10.1055/s-0029-1216639",

language = "English",

pages = "1573--1577",

journal = "Synthesis",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

number = "9",

}

TY - JOUR

T1 - Sulfonyl hydrazine as new functionality in organocatalysis

T2 - Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition

AU - Chen, Ling Yan

AU - He, Hao

AU - Pei, Bao Jian

AU - Chan, Wing Hong

AU - Lee, Albert W.M.

PY - 2009/5

Y1 - 2009/5

N2 - Sulfonyl hydrazine is a new functionality for the Lewis base organocatalysis. Nα-substituted camphorsulfonyl hydrazines (CaSH) are effective organocatalysts for the asymmetric aza-Michael addition to α,β-unsaturated aldehydes with enantioselectivity of up to 90%.

AB - Sulfonyl hydrazine is a new functionality for the Lewis base organocatalysis. Nα-substituted camphorsulfonyl hydrazines (CaSH) are effective organocatalysts for the asymmetric aza-Michael addition to α,β-unsaturated aldehydes with enantioselectivity of up to 90%.

KW - α,β-unsaturated aldehyde

KW - Aza-Michael addition

KW - Camphorsulfonyl hydrazine

KW - Organocatalysis

KW - Sulfonyl hydrazine

UR - http://www.scopus.com/inward/record.url?scp=67650079016&partnerID=8YFLogxK

U2 - 10.1055/s-0029-1216639

DO - 10.1055/s-0029-1216639

M3 - Journal article

AN - SCOPUS:67650079016

SN - 0039-7881

SP - 1573

EP - 1577

JO - Synthesis

JF - Synthesis

IS - 9

M1 - C00609SS

ER -

Sulfonyl hydrazine as new functionality in organocatalysis: Camphorsulfonyl hydrazine catalyzed enantioselective Aza-Michael addition

Abstract

Scopus Subject Areas

User-Defined Keywords

Access to Document

Other files and links

Fingerprint

Cite this