Study on the Prediction Method of Long-term Benign and Malignant Pulmonary Lesions Based on LSTM

Xindong Liu, Mengnan Wang, Rukhma Aftab*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

4 Citations (Scopus)

Abstract

In order to more accurately and comprehensively characterize the changes and development rules of lesion characteristics in pulmonary medical images in different periods, the study was conducted to predict the evolution of pulmonary nodules in the longitudinal dimension of time, and a benign and malignant prediction model of pulmonary lesions in different periods was constructed under multiscale three-dimensional (3D) feature fusion. According to the sequence of computed tomography (CT) images of patients at different stages, 3D interpolation was conducted to generate 3D lung CT images. The 3D features of different size lesions in the lungs were extracted using 3D convolutional neural networks for fusion features. A time-modulated long short-term memory was constructed to predict the benign and malignant lesions by using the improved time-length memory method to learn the feature vectors of lung lesions with temporal and spatial characteristics in different periods. The experiment shows that the area under the curve of the proposed method is 92.71%, which is higher than that of the traditional method.

Original languageEnglish
Article number791424
Number of pages12
JournalFrontiers in Bioengineering and Biotechnology
Volume10
DOIs
Publication statusPublished - 2 Mar 2022

User-Defined Keywords

  • 3D CNNs
  • characteristics of the fusion
  • multiscale three-dimensional feature
  • prediction
  • pulmonary lesions
  • time-modulated LSTM

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