Study on interaction of L-tryptophan with p-sulfonatocalix[4]arene by spectrofluorometry

Wen Ye Li, Ying Li Wei, Wen Ting An, Shao Min Shuang*, Ricky M S WONG

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The interactions between L-tryptophan(L-Trp) and water-soluble p-sulfonatocalix[4]-arene (SCX4) were investigated by spectrofluorometry. The effect of pH was discussed. The interaction process was estimated from the thermodynamic viewpoint. The SCX4 was found to be able to adjust its conformation to fit the size of L-Trp, and the benzene of L-Trp penetrated into the hydrophobic cavity of SCX4. Meanwhile, the binding mechanism was further elucidated by 1HNMR and molecular mechanics calculations.

Original languageEnglish
Pages (from-to)1592-1594
Number of pages3
JournalChinese Chemical Letters
Volume17
Issue number12
Publication statusPublished - Dec 2006

Scopus Subject Areas

  • Chemistry(all)

User-Defined Keywords

  • Fluorescence
  • L-tryptophan
  • P-sulfonatocalix[4]arene

Fingerprint

Dive into the research topics of 'Study on interaction of L-tryptophan with p-sulfonatocalix[4]arene by spectrofluorometry'. Together they form a unique fingerprint.

Cite this