TY - JOUR
T1 - Stereoisomer-Specific Trophodynamics of the Chiral Brominated Flame Retardants HBCD and TBECH in a Marine Food Web, with Implications for Human Exposure
AU - Ruan, Yuefei
AU - Zhang, Xiaohua
AU - Qiu, Jian Wen
AU - Leung, Kenneth M. Y.
AU - Lam, James C. W.
AU - Lam, Paul K. S.
N1 - Funding Information:
This project was jointly supported by the General Research Fund (CityU 11100614 and 11338216), the Early Career Scheme (EdUHK 28300317), and the Collaborative Research Fund (HKU5/CRF/12G) from the Research Grants Council of the Hong Kong SAR Government.
Publisher copyright:
© 2018 American Chemical Society
PY - 2018/8/7
Y1 - 2018/8/7
N2 - Stereoisomers of 1,2,5,6,9,10-hexabromocyclododecane (HBCD) and 1,2-dibromo-4-(1,2-dibromoethyl)-cyclohexane (TBECH) were determined in sediments and 30 marine species in a marine food web to investigate their trophic transfer. Lipid content was found to affect the bioaccumulation of ΣHBCD and ΣTBECH in these species. Elevated biomagnification of each diastereomer from prey species to marine mammals was observed. For HBCD, biota samples showed a shift from γ- to α-HBCD when compared with sediments and technical mixtures; trophic magnification potential of (-)-α- and (+)-α-HBCD were observed in the food web, with trophic magnification factors (TMFs) of 11.8 and 8.7, respectively. For TBECH, the relative abundance of γ- and δ-TBECH exhibited an increasing trend from abiotic matrices to biota samples; trophic magnification was observed for each diastereomer, with TMFs ranging from 1.9 to 3.5. The enantioselective bioaccumulation of the first eluting enantiomer of δ-TBECH in organisms at higher TLs was consistently observed across samples. This is the first report on the trophic transfer of TBECH in the food web. The estimated daily intake of HBCD for Hong Kong residents was approximately 16-times higher than that for the general population in China, and the health risk to local children was high, based on the relevant available reference dose.
AB - Stereoisomers of 1,2,5,6,9,10-hexabromocyclododecane (HBCD) and 1,2-dibromo-4-(1,2-dibromoethyl)-cyclohexane (TBECH) were determined in sediments and 30 marine species in a marine food web to investigate their trophic transfer. Lipid content was found to affect the bioaccumulation of ΣHBCD and ΣTBECH in these species. Elevated biomagnification of each diastereomer from prey species to marine mammals was observed. For HBCD, biota samples showed a shift from γ- to α-HBCD when compared with sediments and technical mixtures; trophic magnification potential of (-)-α- and (+)-α-HBCD were observed in the food web, with trophic magnification factors (TMFs) of 11.8 and 8.7, respectively. For TBECH, the relative abundance of γ- and δ-TBECH exhibited an increasing trend from abiotic matrices to biota samples; trophic magnification was observed for each diastereomer, with TMFs ranging from 1.9 to 3.5. The enantioselective bioaccumulation of the first eluting enantiomer of δ-TBECH in organisms at higher TLs was consistently observed across samples. This is the first report on the trophic transfer of TBECH in the food web. The estimated daily intake of HBCD for Hong Kong residents was approximately 16-times higher than that for the general population in China, and the health risk to local children was high, based on the relevant available reference dose.
UR - http://www.scopus.com/inward/record.url?scp=85049252084&partnerID=8YFLogxK
U2 - 10.1021/acs.est.8b02206
DO - 10.1021/acs.est.8b02206
M3 - Journal article
C2 - 29939731
AN - SCOPUS:85049252084
SN - 0013-936X
VL - 52
SP - 8183
EP - 8193
JO - Environmental Science and Technology
JF - Environmental Science and Technology
IS - 15
ER -
