Spatial proteome profiling by immunohistochemistry-based laser capture microdissection and data-independent acquisition proteomics

Keyphrases

• Accuracy Improvement 12%
• Antibody Targeting 12%
• Bioinformatics Analysis 12%
• Biomedical Research 12%
• Cancer Cells 25%
• Cancer Research 12%
• Cancer-associated Fibroblasts 25%
• Cell Population 12%
• Cell Type Identification 12%
• Cell-Associated 25%
• Chemically Crosslinked 12%
• Clinical Application 12%
• Data-independent Acquisition Proteomics 100%
• Efficiency Improvement 12%
• Eosin 12%
• Eosin Staining 12%
• Hematoxylin 12%
• Hematoxylin Staining 12%
• Hepatocellular Carcinoma Tissues 25%
• High Reproducibility 12%
• High Sensitivity 12%
• Immunohistochemistry 100%
• Laser Capture Microdissection 100%
• Local Cells 12%
• Pathologist 12%
• Post-crosslinking 12%
• Preparation Technology 12%
• Protein Clusters 12%
• Protein Recovery 12%
• Proteome 12%
• Proteome Profiling 100%
• Proteomic Analysis 25%
• Proteomic Approach 12%
• Research Application 12%
• Sample Preparation 12%
• Signaling Molecules 12%
• Spatial Data 12%
• Spatial Profiling 12%
• Spatially Resolved 12%
• Specific Ligands 12%
• Specific Marker 12%
• Specific Receptor 12%
• Targeted Cells 25%
• Tissue Sampling 12%
• Tumor Heterogeneity 12%
• Type-specific 37%

Medicine and Dentistry

• Biomedical Research 12%
• Cancer Associated Fibroblast 25%
• Cancer Cell 25%
• Cancer Research 12%
• Cell Population 12%
• Eosin 25%
• Haematoxylin 25%
• Hepatocellular Carcinoma 25%
• Immunohistochemistry 100%
• Laser Capture Microdissection 100%
• Pathologist 12%
• Proteome 100%
• Proteomics 100%
• Receptor 12%
• Reproducibility 12%
• Signaling Protein 12%
• Tumour Heterogeneity 12%

Biochemistry, Genetics and Molecular Biology

• Bioinformatics 20%
• Cancer Cell 40%
• Eosin 40%
• Fibroblast 40%
• Laser Capture Microdissection 100%
• Proteome 100%
• Proteomics 100%
• Signaling Protein 20%
• Tissue Section 60%