Abstract
This article considers spline smoothing of variance functions. We focus on selection of the smoothing parameters and develop three direct data-driven methods: unbiased risk (UBR), generalized approximate cross-validation (GACV), and generalized maximum likelihood (GML). In addition to guaranteed convergence, simulations show that these direct methods perform better than existing indirect UBR, generalized cross-validation (GCV), and GML methods. The direct UBR and GML methods perform better than the GACV method. An application to array-based comparative genomic hybridization data illustrates the usefulness of the proposed methods.
| Original language | English |
|---|---|
| Pages (from-to) | 312-329 |
| Number of pages | 18 |
| Journal | Journal of Computational and Graphical Statistics |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 2007 |
User-Defined Keywords
- Array-based comparative genomic hybridization
- Generalized approximate cross-validation
- Generalized maximum likelihood
- Heteroscedasticity
- Smoothing parameter
- Unbiased risk
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