Single-molecule kinetics reveals signatures of half-sites reactivity in dihydroorotate dehydrogenase A catalysis

Keyphrases

• Dihydroorotate Dehydrogenase (DHODH) 100%
• Single-molecule Kinetics 100%
• Half-site Reactivity 100%
• Non-fluorescent 40%
• Cooperativity 40%
• Catalytic Activity 20%
• Catalytic Behavior 20%
• Redox State 20%
• Kinetic Analysis 20%
• Intel 20%
• Single Molecule 20%
• Reaction Rate 20%
• Oxidative Half Reaction 20%
• Reaction Kinetics 20%
• Fluorescence Change 20%
• Oxidized State 20%
• Single-molecule Fluorescence 20%
• Catalytic Cooperativity 20%
• Ensemble Averaging 20%
• Reaction Studies 20%
• Dimer Molecules 20%
• Single-molecule Spectroscopy 20%
• Lactococcus Lactis 20%
• Monomeric Enzymes 20%
• Homodimeric 20%
• Flavoenzyme 20%

Biochemistry, Genetics and Molecular Biology

• Dihydroorotate Dehydrogenase 100%
• Cooperation 60%
• Enzyme 40%
• Enzymatic Activity 20%
• Kinetics 20%
• Flavoprotein 20%
• Chemical Reaction Kinetics 20%
• Lactococcus Lactis 20%

Chemistry

• Dihydroorotate 100%
• dimer 60%
• Spectroscopy 20%
• Statistical Ensemble 20%
• Catalyst Activity 20%
• Kinetic Method 20%
• Redox State 20%
• FMN 20%
• Flavoenzyme 20%