Simultaneous determination of methionine cycle metabolites, urea cycle intermediates and polyamines in serum, urine and intestinal tissue by using UHPLC-MS/MS

Keyphrases

• Simultaneous Determination 100%
• High Performance Liquid Chromatography-tandem Mass Spectrometry (HPLC-MS/MS) 100%
• Polyamines 100%
• Urea Cycle 100%
• Intestinal Tissue 100%
• Methionine Cycle 100%
• Acetonitrile 33%
• Method Validation 33%
• Ultra-high Performance Liquid Chromatography (UHPLC) 33%
• MS Method 33%
• Excellent Selectivity 33%
• Arginine 33%
• Ornithine 33%
• Analytical Method 33%
• Mobile Phase 33%
• Derivatization 33%
• Spermidine 33%
• Spermine 33%
• Pathogenic Mechanism 33%
• Metabolomics Study 33%
• Chromatographic Separation 33%
• Biological Matrices 33%
• Biological Samples 33%
• Electrospray Ionization Mass Spectrometry 33%
• Potential Biomarkers 33%
• Polyamine Metabolism 33%
• Formic Acid 33%
• Urine Matrices 33%
• Ion-pairing Agents 33%
• Metabolic Processes 33%
• Matrix Effect 33%
• Retention Behavior 33%
• Reversed-phase Column 33%
• Pathophysiological Mechanisms 33%
• Methionine Metabolism 33%
• Putrescine 33%
• S-adenosylmethionine 33%
• Three-class 33%
• Amide Column 33%
• Citrulline 33%
• Tissue Matrix 33%
• Hyperthyroidism 33%
• Diacetylspermine 33%
• S-adenosylhomocysteine 33%
• Hypothyroidism 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Ultra High Performance Liquid Chromatography 100%
• Polyamine 100%
• Methionine 100%
• Diseases 33%
• Biological Marker 33%
• Arginine 33%
• Ornithine 33%
• Carboxamide 33%
• Acetonitrile 33%
• Formate 33%
• Spermidine 33%
• Spermine 33%
• Putrescine 33%
• S-Adenosyl Methionine 33%
• Citrulline 33%
• Hypothyroidism 33%
• N1 Acetylspermidine 33%
• S Adenosylhomocysteine 33%
• Hyperthyroidism 33%