TY - JOUR
T1 - Simultaneous determination of L-ascorbic acid, dopamine and uric acid with gold nanoparticles-β-cyclodextrin-graphene-modified electrode by square wave voltammetry
AU - Tian, Xianqing
AU - Cheng, Changming
AU - Yuan, Hongyan
AU - Du, Juan
AU - Xiao, Dan
AU - Xie, Shunping
AU - CHOI, Martin M F
N1 - Funding Information:
Financial supports from the Specialized Research Fund for Instrument Program of National Natural Science Foundation of China ( 20927007 ), National Natural Science Foundation of China ( 21175094 and 20803050 ) and the Open Foundation Project of State Key Laboratory of Electronic Thin Films and Integrated Devices of University of Electronic Science and Technology of China ( KFJJ200918 ) are gratefully acknowledged.
PY - 2012/5/15
Y1 - 2012/5/15
N2 - Graphene decorated with gold nanoparticles (AuNPs-β-CD-Gra) has been synthesized by in situ thermal reduction of graphene oxide and HAuCl4 with β-cyclodextrin (β-CD) under alkaline condition. The AuNPs-β-CD-Gra product was well characterized by infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, and selected area electron diffraction. This material was used to fabricate an AuNPs-β-CD-Gra-modified glassy carbon electrode (GCE) which showed excellent electro-oxidation of l-ascorbic acid (AA), dopamine (DA) and uric acid (UA) in 0.10 M NaH2PO 4-HCl buffer solution (pH 2.0) by square wave voltammetry (SWV). Three well-resolved oxidation peaks of AA and DA and UA were obtained. The AuNPs-β-CD-Gra/GCE exhibits linear responses to AA, DA and UA in the ranges 30-2000, 0.5-150 and 0.5-60 μM, respectively. The detection limits (based on S/N = 3 and preconcentration time = 3.0 min) for AA, DA and UA are 10, 0.15 and 0.21 μM, respectively. The AuNPs-β-CD-Gra/GCE has been successfully applied to determine UA in human urine with satisfactory results. Our work provides a simple, convenient and green route to synthesize AuNPs on Gra which is potentially useful in electroanalysis.
AB - Graphene decorated with gold nanoparticles (AuNPs-β-CD-Gra) has been synthesized by in situ thermal reduction of graphene oxide and HAuCl4 with β-cyclodextrin (β-CD) under alkaline condition. The AuNPs-β-CD-Gra product was well characterized by infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, and selected area electron diffraction. This material was used to fabricate an AuNPs-β-CD-Gra-modified glassy carbon electrode (GCE) which showed excellent electro-oxidation of l-ascorbic acid (AA), dopamine (DA) and uric acid (UA) in 0.10 M NaH2PO 4-HCl buffer solution (pH 2.0) by square wave voltammetry (SWV). Three well-resolved oxidation peaks of AA and DA and UA were obtained. The AuNPs-β-CD-Gra/GCE exhibits linear responses to AA, DA and UA in the ranges 30-2000, 0.5-150 and 0.5-60 μM, respectively. The detection limits (based on S/N = 3 and preconcentration time = 3.0 min) for AA, DA and UA are 10, 0.15 and 0.21 μM, respectively. The AuNPs-β-CD-Gra/GCE has been successfully applied to determine UA in human urine with satisfactory results. Our work provides a simple, convenient and green route to synthesize AuNPs on Gra which is potentially useful in electroanalysis.
KW - Dopamine
KW - Electroanalysis
KW - Graphene
KW - l-Ascorbic acid
KW - Uric acid
KW - β-Cyclodextrin
UR - http://www.scopus.com/inward/record.url?scp=84859430703&partnerID=8YFLogxK
U2 - 10.1016/j.talanta.2012.01.047
DO - 10.1016/j.talanta.2012.01.047
M3 - Article
AN - SCOPUS:84859430703
SN - 0039-9140
VL - 93
SP - 79
EP - 85
JO - Talanta
JF - Talanta
ER -