Shear disassembly of hierarchical superparamagnetic Fe3O4 hollow nanoparticle necklace chains

Shouhu Xuan, Lingyun Hao, Ken C F LEUNG*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Supramolecular amide hydrogen-bond interactions between bundles of necklace-like chains based on superparamagnetic hollow Fe3O4 nanoparticle beads could be indirectly quantified by shear stress and magnetorheological analyses. First, a facile magnetic field-induced method was developed for the preparation of the superparamagnetic Fe3O4 hierarchical chain structures. Primary Fe3O4 hollow nanospheres, hollow nanosphere-assembled chains, and partially hollow nanosphere-assembled chains were successfully prepared. These superparamagnetic nanoparticles and chains could be well dispersed in aqueous solutions. The magnetic hollow nanoparticle chains possess a strong magnetorheological effect in aqueous solutions. Bundle wire-like structures based on chains or nanospheres could be formed with different magnetic field alignments. The hollow nanostructure greatly strengthens the as-formed bundle wire-like structures such that the chains have a larger magnetorheological effect than that of the hollow nanospheres. It is envisaged that a specific cell transfection mechanism of chains and wires could involve a partial disassembly from bundles to individual chains/wires before endocytosis. The force that is exerted on this disassembly from bundles to individual chains/wires in a specific medium, which are quantified by shear stress and magnetorheological analyses, would shed light on cell magnetofection mechanisms.

Original languageEnglish
Pages (from-to)6125-6132
Number of pages8
JournalNew Journal of Chemistry
Issue number12
Publication statusPublished - 1 Dec 2014

Scopus Subject Areas

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry


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