Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)

Qian Feng; Xi Chen; Ou Ma; Yingying Liu; Mingxiao Ding; Richard A. Collins; Lung Sang Ko; Jun Xing; Lok Ting Lau; Albert Cheung Hoi Yu; Jianguo Chen

doi:10.1016/S0006-291X(03)00250-X

Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)

Qian Feng, Xi Chen, Ou Ma, Yingying Liu, Mingxiao Ding, Richard A. Collins, Lung Sang Ko, Jun Xing, Lok Ting Lau, Albert Cheung Hoi Yu, Jianguo Chen^*

^*Corresponding author for this work

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22 Citations (Scopus)

Abstract

The nucleotide sequence of the VP1 coding region of foot-and-mouth disease virus (FMDV) strain HKN/2002, isolated from a disease outbreak occurring in Hong Kong in February 2002, was determined and compared with the sequences of other FMDVs. The VP1 coding region was 639 nucleotides in length and encoded a protein of 213 amino acid residues. Comparison of the VP1 nucleotide sequence with those of other isolates indicated that HKN/2002 belonged to serotype O. A VP1-based sequence similarity tree of several South-east Asian FMDV-O isolates showed that HKN/2002 was most closely related to FMDV isolates found in Hong Kong from 1991 to 1999 and Taiwan in 1997. Comparison of the amino acid sequence of the major immunogenic region of HKN/2002 with that of the serotype O vaccine strain, O1/Manisa/Turkey/69, reveals significant similarity, indicating that current serotype O vaccines may offer some degree of protection against HKN/2002.

Original language	English
Pages (from-to)	715-721
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	302
Issue number	4
DOIs	https://doi.org/10.1016/S0006-291X(03)00250-X
Publication status	Published - 21 Mar 2003

Scopus Subject Areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

User-Defined Keywords

Foot-and-mouth disease
Hong Kong
Serotype
VP1 protein

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0006-291X(03)00250-X

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title = "Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)",

abstract = "The nucleotide sequence of the VP1 coding region of foot-and-mouth disease virus (FMDV) strain HKN/2002, isolated from a disease outbreak occurring in Hong Kong in February 2002, was determined and compared with the sequences of other FMDVs. The VP1 coding region was 639 nucleotides in length and encoded a protein of 213 amino acid residues. Comparison of the VP1 nucleotide sequence with those of other isolates indicated that HKN/2002 belonged to serotype O. A VP1-based sequence similarity tree of several South-east Asian FMDV-O isolates showed that HKN/2002 was most closely related to FMDV isolates found in Hong Kong from 1991 to 1999 and Taiwan in 1997. Comparison of the amino acid sequence of the major immunogenic region of HKN/2002 with that of the serotype O vaccine strain, O1/Manisa/Turkey/69, reveals significant similarity, indicating that current serotype O vaccines may offer some degree of protection against HKN/2002.",

keywords = "Foot-and-mouth disease, Hong Kong, Serotype, VP1 protein",

author = "Qian Feng and Xi Chen and Ou Ma and Yingying Liu and Mingxiao Ding and Collins, {Richard A.} and Ko, {Lung Sang} and Jun Xing and Lau, {Lok Ting} and Yu, {Albert Cheung Hoi} and Jianguo Chen",

note = "Funding Information: The authors thank Leslie Sims, Trevor Ellis, Pamela Li Chui Har, David Burrows, and C.C. Chan of the Agriculture, Fisheries and Conservation Department, Veterinary Laboratory Division, Tai Lung Experimental Station, Lin Tong Mei, Sheung Shui, Hong Kong SAR, China, for providing virus samples and technical assistance. This work was supported by Grant G1999011904 from the Special Funds for Major State Basic Research of China to J. Chen. The X. Chen was supported by Jun-Zheng Foundation in PKU. Publisher copyright: {\textcopyright} 2003 Elsevier Science (USA). All rights reserved.",

year = "2003",

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doi = "10.1016/S0006-291X(03)00250-X",

language = "English",

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journal = "Biochemical and Biophysical Research Communications",

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T1 - Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)

AU - Feng, Qian

AU - Chen, Xi

AU - Ma, Ou

AU - Liu, Yingying

AU - Ding, Mingxiao

AU - Collins, Richard A.

AU - Ko, Lung Sang

AU - Xing, Jun

AU - Lau, Lok Ting

AU - Yu, Albert Cheung Hoi

AU - Chen, Jianguo

N1 - Funding Information: The authors thank Leslie Sims, Trevor Ellis, Pamela Li Chui Har, David Burrows, and C.C. Chan of the Agriculture, Fisheries and Conservation Department, Veterinary Laboratory Division, Tai Lung Experimental Station, Lin Tong Mei, Sheung Shui, Hong Kong SAR, China, for providing virus samples and technical assistance. This work was supported by Grant G1999011904 from the Special Funds for Major State Basic Research of China to J. Chen. The X. Chen was supported by Jun-Zheng Foundation in PKU. Publisher copyright: © 2003 Elsevier Science (USA). All rights reserved.

PY - 2003/3/21

Y1 - 2003/3/21

N2 - The nucleotide sequence of the VP1 coding region of foot-and-mouth disease virus (FMDV) strain HKN/2002, isolated from a disease outbreak occurring in Hong Kong in February 2002, was determined and compared with the sequences of other FMDVs. The VP1 coding region was 639 nucleotides in length and encoded a protein of 213 amino acid residues. Comparison of the VP1 nucleotide sequence with those of other isolates indicated that HKN/2002 belonged to serotype O. A VP1-based sequence similarity tree of several South-east Asian FMDV-O isolates showed that HKN/2002 was most closely related to FMDV isolates found in Hong Kong from 1991 to 1999 and Taiwan in 1997. Comparison of the amino acid sequence of the major immunogenic region of HKN/2002 with that of the serotype O vaccine strain, O1/Manisa/Turkey/69, reveals significant similarity, indicating that current serotype O vaccines may offer some degree of protection against HKN/2002.

AB - The nucleotide sequence of the VP1 coding region of foot-and-mouth disease virus (FMDV) strain HKN/2002, isolated from a disease outbreak occurring in Hong Kong in February 2002, was determined and compared with the sequences of other FMDVs. The VP1 coding region was 639 nucleotides in length and encoded a protein of 213 amino acid residues. Comparison of the VP1 nucleotide sequence with those of other isolates indicated that HKN/2002 belonged to serotype O. A VP1-based sequence similarity tree of several South-east Asian FMDV-O isolates showed that HKN/2002 was most closely related to FMDV isolates found in Hong Kong from 1991 to 1999 and Taiwan in 1997. Comparison of the amino acid sequence of the major immunogenic region of HKN/2002 with that of the serotype O vaccine strain, O1/Manisa/Turkey/69, reveals significant similarity, indicating that current serotype O vaccines may offer some degree of protection against HKN/2002.

KW - Foot-and-mouth disease

KW - Hong Kong

KW - Serotype

KW - VP1 protein

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U2 - 10.1016/S0006-291X(03)00250-X

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AN - SCOPUS:0037459177

SN - 0006-291X

VL - 302

SP - 715

EP - 721

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 4

ER -

Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)

Abstract

Scopus Subject Areas

User-Defined Keywords

UN SDGs

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